Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CTSK | P43235 | 2/20 | 0.45 |
| ▸ | KLK7 | P49862 | 1/20 | 0.45 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
| ▸ | CTSS | P25774 | 1/20 | 0.43 |
| ▸ | PREP | P48147 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7450687 | 0.92 | KMT2A (0.43) | TSHRCYP3A4MAPTCYP2C9RAB9A | |
| SCHEMBL7450693 | 0.92 | KMT2A (0.43) | TSHRCYP3A4MAPTCYP2C9RAB9A | |
| SCHEMBL8574927 | 0.90 | CTSK (0.46) | TSHRCYP3A4MAPTCYP2C9RAB9A | |
| SCHEMBL8110299 | 0.90 | CTSK (0.44) | TSHRCYP3A4MAPTCYP2C9RAB9A | |
| SCHEMBL8102832 | 0.89 | CTRB1 (0.42) | TSHRCYP3A4MAPTCYP2C9RAB9A | |
| SCHEMBL7455094 | 0.89 | CTRB1 (0.42) | TSHRCYP3A4MAPTCYP2C9RAB9A | |
| SCHEMBL7455087 | 0.89 | CTRB1 (0.42) | TSHRCYP3A4MAPTCYP2C9RAB9A | |
| SCHEMBL8102837 | 0.89 | CTRB1 (0.42) | TSHRCYP3A4MAPTCYP2C9RAB9A | |
| SCHEMBL8438142 | 0.88 | HSD11B1 (0.41) | MAPTRAB9AKMT2ALMNAALDH1A1 | |
| SCHEMBL8438547 | 0.88 | HSD11B1 (0.41) | MAPTRAB9AKMT2ALMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5866564-A | STABILITY | SANKYO COMPANY, LIMITED (JP) | 1999-02-02 | — | — | US | disclosed |