Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.43 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 6/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5724167 | 0.86 | ALDH1A1 (0.67) | ALDH1A1MAPTLMNASMN1; SMN2GPR119 | |
| SCHEMBL8435707 | 0.82 | DPP8 (0.48) | ALDH1A1MAPTLMNASMN1; SMN2DPP8 | |
| SCHEMBL27536768 | 0.80 | ALDH1A1 (0.48) | ALDH1A1MAPT | |
| SCHEMBL5724452 | 0.79 | ALDH1A1 (0.50) | ALDH1A1MAPTLMNADPP8DPP9 | |
| Trifluoroacetic Acid SCHEMBL8439463 | 0.78 | KCNJ1 (0.44) | ALDH1A1MAPTDPP8DPP9KMT2A | |
| SCHEMBL2388312 | 0.77 | ALDH1A1 (0.67) | ALDH1A1MAPTLMNASMN1; SMN2KMT2A | |
| SCHEMBL377491 | 0.77 | ALDH1A1 (0.67) | ALDH1A1MAPTLMNASMN1; SMN2 | |
| SCHEMBL8449180 | 0.77 | ALDH1A1 (0.47) | ALDH1A1MAPTLMNASMN1; SMN2DPP8 | |
| SCHEMBL7463372 | 0.77 | ALDH1A1 (0.47) | ALDH1A1MAPTLMNASMN1; SMN2DPP8 | |
| SCHEMBL8435893 | 0.76 | DPP8 (0.41) | ALDH1A1MAPTLMNASMN1; SMN2DPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5866564-A | STABILITY | SANKYO COMPANY, LIMITED (JP) | 1999-02-02 | — | — | US | disclosed |
| EP-0560613-B1 | Antimicrobial carbapenem derivatives, their preparation and their therapeutic use | SANKYO CO (JP) | 1998-11-25 | — | — | EP | disclosed |
| US-5712267-A | Carbapenem derivatives, their preparation and their use as antibiotics | SANKYO COMPANY,. LIMITED (JP) | 1998-01-27 | — | — | US | disclosed |
| EP-0560613-A1 | Antimicrobial carbapenem derivatives, their preparation and their therapeutic use | SANKYO COMPANY LIMITED (JP) | 1993-09-15 | — | — | EP | disclosed |