Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNJ1 | P48048 | 2/20 | 0.44 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.44 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TGM2 | P21980 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8435707 | 0.93 | DPP8 (0.48) | KCNJ1DPP8DPP9KCNH2KDM4E | |
| Trifluoroacetic Acid SCHEMBL8438033 | 0.81 | KCNJ1 (0.47) | KCNJ1DPP8DPP9KCNH2KDM4E | |
| SCHEMBL8440339 | 0.78 | ALDH1A1 (0.59) | DPP8DPP9P2RX7ALDH1A1MAPT | |
| SCHEMBL6944079 | 0.77 | DPP8 (0.52) | KCNJ1DPP8DPP9KCNH2KDM4E | |
| Trifluoroacetic Acid SCHEMBL8435341 | 0.76 | KCNJ1 (0.48) | KCNJ1KCNH2KDM4EALDH1A1MAPT | |
| SCHEMBL3039451 | 0.76 | KCNJ1 (0.53) | KCNJ1DPP8DPP9KCNH2KDM4E | |
| Hydrochloric Acid SCHEMBL5724126 | 0.75 | KCNJ1 (0.52) | KCNJ1DPP8DPP9KCNH2KDM4E | |
| Trifluoroacetic Acid SCHEMBL6046649 | 0.74 | KCNJ1 (0.48) | KCNJ1DPP8DPP9KCNH2KDM4E | |
| Trifluoroacetic Acid SCHEMBL8438721 | 0.74 | EPHX1 (0.46) | KCNJ1ALDH1A1TGM2 | |
| Trifluoroacetic Acid SCHEMBL8439864 | 0.74 | EPHX1 (0.46) | KCNJ1ALDH1A1TGM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5866564-A | STABILITY | SANKYO COMPANY, LIMITED (JP) | 1999-02-02 | — | — | US | disclosed |
| EP-0560613-B1 | Antimicrobial carbapenem derivatives, their preparation and their therapeutic use | SANKYO CO (JP) | 1998-11-25 | — | — | EP | disclosed |
| US-5712267-A | Carbapenem derivatives, their preparation and their use as antibiotics | SANKYO COMPANY,. LIMITED (JP) | 1998-01-27 | — | — | US | disclosed |
| EP-0560613-A1 | Antimicrobial carbapenem derivatives, their preparation and their therapeutic use | SANKYO COMPANY LIMITED (JP) | 1993-09-15 | — | — | EP | disclosed |