Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.32 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.32 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.32 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.31 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1552746 | 0.87 | CYP19A1 (0.38) | TSHRGAA | |
| SCHEMBL9165314 | 0.86 | KDM4E (0.39) | ALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL8110564 | 0.86 | S1PR1 (0.34) | L3MBTL1ALDH1A1TSHRSMN1; SMN2MAPK1 | |
| SCHEMBL4078370 | 0.74 | TSHR (0.48) | L3MBTL1ALDH1A1TSHRIMPDH2IMPDH1 | |
| SCHEMBL9165041 | 0.72 | TOP2A (0.37) | GAA | |
| SCHEMBL4128351 | 0.71 | ALDH1A1 (0.34) | L3MBTL1ALDH1A1TSHRIMPDH2IMPDH1 | |
| SCHEMBL1507799 | 0.70 | CYP19A1 (0.46) | ALDH1A1TSHR | |
| SCHEMBL27859305 | 0.68 | ESR2 (0.41) | L3MBTL1ALDH1A1TSHRMAPK1IMPDH2 | |
| SCHEMBL4098531 | 0.67 | ALDH1A1 (0.45) | L3MBTL1ALDH1A1TSHRSGMS2GAA | |
| SCHEMBL8767389 | 0.65 | CYP19A1 (0.41) | ALDH1A1TSHRSMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5945109-A | CONSISTS OF AROMATASE INHIBITORS AND ANTIESTROGENS SELECTED FROM TAMOXIFEN AND HYDROXYTAMOXIFEN/4-/ TO REDUCE SUBCUTANEOUS FATTY TISSUES SUCH AS CELLULITE | S.W. PATENTVERWERTUNGS GES.M.B.H. (AT) | 1999-08-31 | — | — | US | disclosed |