Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8433624 | 0.87 | — | — | |
| SCHEMBL8423689 | 0.77 | MAPT (0.30) | MAPT | |
| SCHEMBL8437513 | 0.69 | MAPT (0.31) | MAPT | |
| SCHEMBL8438668 | 0.67 | — | — | |
| SCHEMBL8435374 | 0.65 | HIF1A (0.35) | MAPTHIF1A | |
| SCHEMBL8303039 | 0.61 | NR5A1 (0.33) | — | |
| SCHEMBL8437979 | 0.60 | MAPT (0.38) | MAPTHIF1A | |
| SCHEMBL8427259 | 0.59 | MAPT (0.40) | MAPTHIF1A | |
| SCHEMBL9998388 | 0.55 | ESR2 (0.55) | — | |
| SCHEMBL9618499 | 0.54 | MAPT (0.46) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0824521-B1 | 1-FLUOR-6,7-DIHYDRO-5H-ISOQUINOLINE-8-ONE-DERIVATIVES AND THE USE THEREOF IN LIQUID CRYSTALLINE MIXTURES | AVENTIS RES & TECH GMBH & CO (DE) | 1999-12-01 | — | — | EP | disclosed |
| US-5874023-A | ELECTROOPTICS, DISPLAYS | HOECHST AKTIENGESELLSCHAFT (DE) | 1999-02-23 | — | — | US | disclosed |
| EP-0824521-A1 | 1-FLUOR-6,7-DIHYDRO-5H-ISOQUINOLINE-8-ONE-DERIVATIVES AND THE USE THEREOF IN LIQUID CRYSTALLINE MIXTURES | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-02-25 | — | — | EP | disclosed |
| WO-1996035673-A1 | 1-FLUOR-6,7-DIHYDRO-5H-ISOQUINOLINE-8-ONE-DERIVATIVES AND THE USE THEREOF IN LIQUID CRYSTALLINE MIXTURES | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-11-14 | — | — | WO | disclosed |