Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8438668 | 0.87 | — | — | |
| SCHEMBL8299252 | 0.83 | NR5A1 (0.32) | — | |
| SCHEMBL8440460 | 0.77 | MAPT (0.30) | MAPT | |
| SCHEMBL8293978 | 0.70 | CNR2 (0.32) | — | |
| SCHEMBL8437513 | 0.69 | MAPT (0.31) | MAPT | |
| SCHEMBL8433624 | 0.67 | — | — | |
| SCHEMBL8435374 | 0.65 | HIF1A (0.35) | MAPT | |
| SCHEMBL8303039 | 0.61 | NR5A1 (0.33) | — | |
| SCHEMBL8427259 | 0.61 | MAPT (0.40) | MAPT | |
| SCHEMBL8437979 | 0.60 | MAPT (0.38) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0828716-B1 | TRIFLUORTETRAHYDRO-ISOQUINOLINE DERIVATIVES AND THE USE THEREOF IN LIQUID CRYSTALLINE MIXTURES | AVENTIS RES & TECH GMBH & CO (DE) | 1999-12-01 | — | — | EP | disclosed |
| US-5904877-A | CHEMICAL, THERMAL AND LIGHT STABILITY | HOECHST AKTIENGESELLSCHAFT (DE) | 1999-05-18 | — | — | US | disclosed |