Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP1 | P22413 | 2/20 | 0.39 |
| ▸ | RET | P07949 | 10/20 | 0.37 |
| ▸ | SRC | P12931 | 3/20 | 0.37 |
| ▸ | LCK | P06239 | 1/20 | 0.37 |
| ▸ | TEK | Q02763 | 1/20 | 0.37 |
| ▸ | FLT3 | P36888 | 2/20 | 0.36 |
| ▸ | NT5E | P21589 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7700383 | 0.88 | NPC1 (0.43) | ENPP1RETSRCLCKTEK | |
| SCHEMBL7703236 | 0.86 | ADK (0.38) | RETSRCLCKTEKFLT3 | |
| SCHEMBL8991249 | 0.85 | ADK (0.33) | ENPP1SRCFLT3 | |
| SCHEMBL8991270 | 0.79 | IGF1R (0.43) | RETSRCLCKTEK | |
| SCHEMBL8991287 | 0.78 | FLT3 (0.40) | ENPP1RETSRCLCKTEK | |
| SCHEMBL7700384 | 0.78 | ENPP1 (0.39) | ENPP1RETSRCLCKTEK | |
| SCHEMBL7701195 | 0.77 | ADK (0.42) | ENPP1RETSRCLCKTEK | |
| SCHEMBL8991118 | 0.76 | RET (0.38) | ENPP1RET | |
| SCHEMBL10388752 | 0.76 | NPC1 (0.47) | ENPP1SRCLCKTEKFLT3 | |
| SCHEMBL8440532 | 0.75 | SRC (0.41) | RETSRCLCKTEKFLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5543413-A | VIRAL ACTIVITY AGAINST HUMAN CYTOMEGALOVIRUS AND HERPES SIMPLEX VIRUS | REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 1996-08-06 | — | — | US | disclosed |