Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8521719 | 0.81 | NPC1 (0.34) | NPC1TSHRRAB9ASMN1; SMN2SMYD3 | |
| SCHEMBL8435850 | 0.80 | MAPK14 (0.33) | MAPK14 | |
| SCHEMBL8435003 | 0.79 | RAB9A (0.35) | NPC1TSHRRAB9ASMN1; SMN2SMYD3 | |
| SCHEMBL9076104 | 0.79 | NPC1 (0.42) | NPC1TSHRRAB9ASMN1; SMN2SMYD3 | |
| SCHEMBL8436037 | 0.72 | IDH1 (0.38) | NPC1TSHRRAB9ASMN1; SMN2SMYD3 | |
| SCHEMBL9077297 | 0.71 | NPC1 (0.42) | NPC1TSHRRAB9ASMN1; SMN2SMYD3 | |
| SCHEMBL8438552 | 0.68 | SMN1; SMN2 (0.42) | NPC1TSHRRAB9ASMN1; SMN2SMYD3 | |
| SCHEMBL9078260 | 0.68 | LMNA (0.36) | TSHRRAB9AMAPK14HTTLMNA | |
| SCHEMBL9075629 | 0.67 | MAPK14 (0.33) | MAPK14 | |
| SCHEMBL9074668 | 0.62 | NPC1 (0.43) | NPC1TSHRRAB9ASMN1; SMN2SMYD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0669326-B1 | Cyanoisoxazoles | BASF AG (DE) | 1999-12-22 | — | — | EP | disclosed |
| EP-0669326-A1 | Cyanoisoxazoles | BASF Aktiengesellschaft (DE) | 1995-08-30 | — | — | EP | disclosed |