SCHEMBL3255241

SCHEMBL3255241

Nc1cccc2sc(C(=O)O)cc12

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCL2L1 Q07817 1/20 0.53
SLC9A1 P19634 8/20 0.45
PLK4 O00444 2/20 0.45
AURKA O14965 2/20 0.45
DAPK3 O43293 2/20 0.45
CHEK2 O96017 2/20 0.45
CDK1 P06493 2/20 0.45
PIM1 P11309 2/20 0.45
CDK2 P24941 2/20 0.45
MAPK9 P45984 2/20 0.45
CSNK1D P48730 2/20 0.45
GSK3A P49840 2/20 0.45
GSK3B P49841 2/20 0.45
CSNK2A1 P68400 2/20 0.45
DYRK1A Q13627 2/20 0.45
AURKB Q96GD4 2/20 0.45
PLK3 Q9H4B4 2/20 0.45
PIM2 Q9P1W9 2/20 0.45
PRKACA P17612 1/20 0.45
RPS6KA3 P51812 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL828815 0.83 ALDH1A1 (0.51) SLC9A1CSNK1DGSK3AGSK3BCSNK2A1
SCHEMBL29749510 0.83 ALDH1A1 (0.51) SLC9A1CSNK1DGSK3AGSK3BCSNK2A1
SCHEMBL11660706 0.80 BCL2L1 (0.55) BCL2L1SLC9A1PLK4AURKADAPK3
SCHEMBL2893037 0.80 SLC9A1 (0.62) BCL2L1SLC9A1PLK4AURKADAPK3
SCHEMBL826041 0.79 SLC9A1 (0.74) SLC9A1
SCHEMBL8440564 0.79 PLAU (0.63) BCL2L1SLC9A1PLK4AURKADAPK3
SCHEMBL699799 0.79 HDAC3 (0.71) BCL2L1SLC9A1PLK4AURKADAPK3
SCHEMBL1091931 0.79 SLC9A1 (0.63) BCL2L1SLC9A1PLK4AURKADAPK3
SCHEMBL29485573 0.79 HDAC3 (0.71) BCL2L1SLC9A1PLK4AURKADAPK3
SCHEMBL13709504 0.79 F9 (0.68) SLC9A1F9PLAUF10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9955689-B2 Method for promoting plant growth SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-05-01 US disclosed
US-9955689-B2 Method for promoting plant growth SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-05-01 US disclosed
US-9955689-B2 Method for promoting plant growth SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-05-01 US disclosed
US-20150289506-A1 METHOD FOR PROMOTING PLANT GROWTH SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-10-15 US disclosed
US-20150289506-A1 METHOD FOR PROMOTING PLANT GROWTH SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-10-15 US disclosed
US-20150289506-A1 METHOD FOR PROMOTING PLANT GROWTH SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-10-15 US disclosed
EP-2926660-A1 METHOD FOR PROMOTING PLANT GROWTH Sumitomo Chemical Company Limited (JP) 2015-10-07 EP disclosed
EP-2926660-A1 METHOD FOR PROMOTING PLANT GROWTH Sumitomo Chemical Company Limited (JP) 2015-10-07 EP disclosed
WO-2014073623-A1 METHOD FOR PROMOTING PLANT GROWTH 住友化学株式会社 (JP) 2014-05-15 WO disclosed
EP-1497278-B1 HETEROCYCLIC AMIDE DERIVATIVES AS CYTOKINE INHIBITORS BOEHRINGER INGELHEIM PHARMA (US) 2010-05-26 EP disclosed
US-7550461-B2 Benzofuran and benzothiophene compounds useful in treating cytokine mediated diseases BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) 2009-06-23 US disclosed
EP-1497278-A1 HETEROCYCLIC AMIDE DERIVATIVES AS CYTOKINE INHIBITORS BOEHRINGER INGELHEIM PHARMACEUTICALS INC. (US) 2005-01-19 EP disclosed
US-20040204417-A1 Novel benzothienyl or indole derivatives, preparation and use thereof as inhibitors of prenyl transferase proteins PIERRE FABRE MEDICAMENT (FR) 2004-10-14 US disclosed
EP-1395581-A2 NOVEL BENZOTHIENYL OR INDOLE DERIVATIVES, PREPARATION AND USE THEREOF AS INHIBITORS OF PRENYL TRANSFERASE PROTEINS PIERRE FABRE MEDICAMENT (FR) 2004-03-10 EP disclosed
US-20030225053-A1 Compounds useful in treating cytokine mediated diseases BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. 2003-12-04 US disclosed
WO-2003087085-A1 HETEROCYCLIC AMIDE DERIVATIVES AS CYTOKINE INHIBITORS BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) 2003-10-23 WO disclosed
WO-2002098852-A2 NOVEL BENZOTHIENYL OR INDOLE DERIVATIVES, AND USE THEREOF AS INHIBITORS OF PRENYL TRANSFERASE PROTEINS PIERRE FABRE MEDICAMENT (FR) 2002-12-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150289506-A1 METHOD FOR PROMOTING PLANT GROWTH FGF2, BROX, BOLA2; BOLA2B BCL2L1 2137/4885SLC9A1 1138/4885PLK4 2178/4885
US-20030225053-A1 Compounds useful in treating cytokine mediated diseases IL6, IL1A, IL1B BCL2L1 997/4885SLC9A1 4385/4885PLK4 3760/4885
US-20040204417-A1 Novel benzothienyl or indole derivatives, preparation and use thereof as inhibitors of prenyl transferase proteins CBR1, CBR3, HCCS BCL2L1 4548/4885SLC9A1 3547/4885PLK4 2630/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.