SCHEMBL4801146

SCHEMBL4801146

CC(=O)OOCC(O)CO

nearest known ligand 0.39

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.39
KDM4E B2RXH2 2/20 0.39
DUSP3 P51452 1/20 0.39
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
USP2 O75604 1/20 0.35
ALDH1A1 P00352 1/20 0.35
DGKA P23743 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
CYP1A2 P05177 2/20 0.32
AGTR1 P30556 1/20 0.32
FAAH O00519 2/20 0.32
PLA2G2C Q5R387 1/20 0.31
AR P10275 1/20 0.31
TSHR P16473 1/20 0.31
MAPK1 P28482 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28363636 0.83 LMNA (0.37) LMNAKDM4EDUSP3MEN1KMT2A
Acetic Acid SCHEMBL27310520 0.81 LMNA (0.41) LMNAKDM4EDUSP3MEN1KMT2A
SCHEMBL2927266 0.79 TSHR (0.42) LMNAKDM4EDUSP3MEN1KMT2A
SCHEMBL4808325 0.78 LMNA (0.44) LMNAKDM4EDUSP3MEN1KMT2A
SCHEMBL7525692 0.77 LMNA (0.44) LMNAKDM4EUSP2SMN1; SMN2
SCHEMBL33457 0.76
SCHEMBL19560102 0.76
SCHEMBL29619673 0.76
SCHEMBL2383959 0.76 LMNA (0.50) LMNAKDM4EDUSP3MEN1KMT2A
SCHEMBL3380530 0.76 LMNA (0.34) LMNAKDM4EDUSP3MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7235229-B2 Clear, stable, dry-and-non-sticky antiperspirant having a select group of polar silicone emollients THE PROCTER & GAMBLE COMPANY (US) 2007-06-26 US claimed
EP-1562541-A1 CLEAR, STABLE, DRY-AND-NON-STICKY ANTIPERSPIRANT HAVING A SELECT GROUP OF POLAR SILICONE EMOLLIENTS THE PROCTER & GAMBLE COMPANY (US) 2005-08-17 EP claimed
US-20040247546-A1 Clear, stable, dry-and-non-sticky antiperspirant having a select group of polar silicone emollients THE PROCTER & GAMBLE COMPANY 2004-12-09 US claimed
WO-2004047786-A1 CLEAR, STABLE, DRY-AND-NON-STICKY ANTIPERSPIRANT HAVING A SELECT GROUP OF POLAR SILICONE EMOLLIENTS THE PROCTER & GAMBLE COMPANY (US) 2004-06-10 WO claimed
US-20030026773-A1 Anhydrous liquid antiperspirant emulsions THE PROCTER & GAMBLE COMPANY 2003-02-06 US claimed
WO-2003002082-A1 PRESSURIZED ANHYDROUS ANTIPERSPIRANT EMULSIONS THE PROCTER & GAMBLE COMPANY (US) 2003-01-09 WO claimed
US-20030007935-A1 STABLE PRESSURIZED ANTIPERSPIRANT COMPOSITIONS CONTAINING DIMETHYLETHER PROPELLANT AND A LOW POLARITY SOLVENT THE PROCTER & GAMBLE COMPANY 2003-01-09 US claimed
US-6485715-B1 Stable pressurized antiperspirant compositions containing dimethylether propellant and a low polarity solvent THE PROCTOR & GAMBLE COMPANY 2002-11-26 US claimed
US-6416750-B1 MIXING ALUMINUM CHLOROHYDRATE, WATER, AND DIOL SOLVENT, SPRAY DRYING TO FORM POWDER, AND DISSOLVING INTO 1,2-DIOL SOLVENT (1,2-HEXANEDIOL); INCREASED FORMULATION FLEXIBILITY; LESS ENERGY INTENSIVE PROCESS SOMERVILLE TECHNOLOGY GROUP, INC. 2002-07-09 US claimed
US-6399049-B1 LIQUID 1,2-HYDROXYALKYL AMIDE, ESTER, ETHER, SILICONE OR ALKYL COMPOUND CARRIERS; NONIRRITATING; THE PROCTER & GAMBLE COMPANY 2002-06-04 US claimed
EP-1206238-A2 COMPOSITIONS CONTAINING SOLUBILIZED ANTIPERSPIRANT ACTIVE THE PROCTER & GAMBLE COMPANY (US) 2002-05-22 EP claimed
EP-1206237-A1 COMPOSITIONS CONTAINING SOLUBILIZED, ACID-ENHANCED ANTIPERSPIRANT ACTIVE THE PROCTER & GAMBLE COMPANY (US) 2002-05-22 EP claimed
WO-2001013872-A1 COMPOSITIONS CONTAINING SOLUBILIZED, ACID-ENHANCED ANTIPERSPIRANT ACTIVE THE PROCTER & GAMBLE COMPANY (US) 2001-03-01 WO claimed
WO-2001013869-A2 COMPOSITIONS CONTAINING SOLUBILIZED ANTIPERSPIRANT ACTIVE THE PROCTER & GAMBLE COMPANY (US) 2001-03-01 WO claimed
US-6126928-A Compositions containing solubilized, acid-enhanced antiperspirant active THE PROCTER & GAMBLE COMPANY (US) 2000-10-03 US claimed
US-20230181435-A1 PIGMENT SUSPENSION AND COSMETIC AGENT PREPARED USING THE PIGMENT SUSPENSION HENKEL AG & CO. KGAA (DE) 2023-06-15 US disclosed
EP-4117615-A1 PIGMENT SUSPENSION AND COSMETIC AGENT PREPARED USING THE PIGMENT SUSPENSION Henkel AG & Co. KGaA (DE) 2023-01-18 EP disclosed
US-6126928-A Compositions containing solubilized, acid-enhanced antiperspirant active THE PROCTER & GAMBLE COMPANY (US) 2000-10-03 US disclosed
EP-0837903-A1 MELTPROCESSIBLE STARCH COMPOSITION, A PROCESS FOR THE PREPARATION THEREOF AND THE USE OF THE COMPOSITION VALTION TEKNILLINEN TUTKIMUSKESKUS (FI) 1998-04-29 EP disclosed
WO-1997003121-A1 MELTPROCESSIBLE STARCH COMPOSITION, A PROCESS FOR THE PREPARATION THEREOF AND THE USE OF THE COMPOSITION VALTION TEKNILLINEN TUTKIMUSKESKUS (FI) 1997-01-30 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030007935-A1 STABLE PRESSURIZED ANTIPERSPIRANT COMPOSITIONS CONTAINING DIMETHYLETHER PROPELLANT AND A LOW POLARITY SOLVENT CDIPT, SIGMAR1, PHOSPHO1 LMNA 2490/4885KDM4E 568/4885DUSP3 80/4885
US-20230181435-A1 PIGMENT SUSPENSION AND COSMETIC AGENT PREPARED USING THE PIGMENT SUSPENSION TYR, EYA3, RB1 LMNA 1170/4885KDM4E 4099/4885DUSP3 2111/4885
US-20040247546-A1 Clear, stable, dry-and-non-sticky antiperspirant having a select group of polar silicone emollients SIGMAR1, SPTAN1, ELOVL1 LMNA 3000/4885KDM4E 946/4885DUSP3 989/4885
US-20030026773-A1 Anhydrous liquid antiperspirant emulsions CUTA, NONO, SIGMAR1 LMNA 3835/4885KDM4E 2575/4885DUSP3 91/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.