Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.66 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.62 |
| ▸ | ADRB2 | P07550 | 7/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.57 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.57 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.57 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.57 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.57 |
| ▸ | HTR2A | P28223 | 1/20 | 0.57 |
| ▸ | MC4R | P32245 | 1/20 | 0.57 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.57 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.57 |
| ▸ | MC3R | P41968 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14521880 | 1.00 | SIGMAR1 (0.66) | SIGMAR1SLC6A4ADRB2CYP3A4MAPK1 | |
| SCHEMBL26969037 | 1.00 | SIGMAR1 (0.66) | SIGMAR1SLC6A4ADRB2CYP3A4MAPK1 | |
| SCHEMBL10662965 | 0.85 | SIGMAR1 (0.68) | SIGMAR1SLC6A4ADRB2CYP3A4MAPK1 | |
| SCHEMBL19012043 | 0.82 | SIGMAR1 (0.68) | SIGMAR1SLC6A4CYP3A4CYP2D6TSHR | |
| SCHEMBL5269077 | 0.81 | SIGMAR1 (0.61) | SIGMAR1SLC6A4ADRB2CYP3A4MAPK1 | |
| SCHEMBL18181945 | 0.81 | OPRK1 (0.66) | SIGMAR1SLC6A4ADRB2CYP3A4MAPK1 | |
| SCHEMBL8882092 | 0.81 | SLC6A4 (0.68) | SIGMAR1SLC6A4ADRB2CYP3A4MAPK1 | |
| SCHEMBL4680337 | 0.80 | SIGMAR1 (0.66) | SIGMAR1SLC6A4CYP3A4CYP2D6TSHR | |
| SCHEMBL31545550 | 0.80 | SIGMAR1 (0.66) | SIGMAR1SLC6A4CYP3A4SLC6A2CYP2D6 | |
| SCHEMBL22249109 | 0.80 | SIGMAR1 (0.66) | SIGMAR1SLC6A4CYP3A4CYP2D6TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070275964-A1 | CANNABINOID RECEPTOR LIGANDS AND USES THEREOF | PFIZER, INC. | 2007-11-29 | — | — | US | disclosed |
| US-7268133-B2 | Cannabinoid receptor ligands and uses thereof | PFIZER, INC. PATENT DEPARTMENT (US) | 2007-09-11 | — | — | US | disclosed |
| US-20040214837-A1 | Cannabinoid receptor ligands and uses thereof | PFIZER INC. | 2004-10-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040214837-A1 | Cannabinoid receptor ligands and uses thereof | CNR1, CNR2, GPR18 | SIGMAR1 102/4885SLC6A4 1093/4885ADRB2 125/4885 |
| US-20070275964-A1 | CANNABINOID RECEPTOR LIGANDS AND USES THEREOF | CNR1, CNR2, GPR18 | SIGMAR1 133/4885SLC6A4 1066/4885ADRB2 139/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.