Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9560262 | 0.78 | MGLL (0.43) | MAPT | |
| SCHEMBL3538727 | 0.72 | ACHE (0.39) | — | |
| SCHEMBL1787694 | 0.70 | — | — | |
| SCHEMBL11022521 | 0.69 | — | — | |
| SCHEMBL14370062 | 0.65 | PIK3CD (0.47) | — | |
| SCHEMBL9825290 | 0.65 | KMT2A (0.43) | — | |
| SCHEMBL2493043 | 0.65 | PIK3CD (0.47) | — | |
| SCHEMBL7609502 | 0.64 | ALDH1A1 (0.32) | MAPT | |
| SCHEMBL3943706 | 0.64 | L3MBTL1 (0.47) | — | |
| SCHEMBL15884956 | 0.63 | GAA (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5998452-A | CARDIOVASCULAR DISORDERS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1999-12-07 | — | — | US | disclosed |
| EP-0799614-A1 | REMEDY FOR ISCHEMIC DISEASES | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1997-10-08 | — | — | EP | disclosed |
| EP-0203743-B1 | OXOTHIAZOLIDINE COMPOUND | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-02-06 | — | — | EP | disclosed |
| US-4764514-A | COGNITIONACTIVATORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-08-16 | — | — | US | disclosed |
| EP-0203743-A1 | Oxothiazolidine compound | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1986-12-03 | — | — | EP | disclosed |