Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.41 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.41 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 4/20 | 0.40 |
| ▸ | MAOA | P21397 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8438210 | 0.68 | TSHR (0.48) | MAOBALDH1A1HTTKDM4EHPGD | |
| SCHEMBL8439784 | 0.68 | ESR2 (0.52) | MAOBALDH1A1KDM4ESMN1; SMN2NPC1 | |
| SCHEMBL8439931 | 0.68 | VKORC1 (0.50) | MAOBMAOAALDH1A1KDM4EHPGD | |
| SCHEMBL8440161 | 0.62 | MAOB (0.51) | MAOBMAOAALDH1A1KDM4EHPGD | |
| SCHEMBL11842666 | 0.60 | ESR2 (0.52) | ALDH1A1KDM4EHPGDSMN1; SMN2POLB | |
| SCHEMBL9208567 | 0.60 | MAOB (0.48) | MAOBMAOAALDH1A1KDM4EHPGD | |
| SCHEMBL705488 | 0.59 | TAS1R3 (1.00) | TAS1R3TAS1R1TAS1R2ALDH1A1HTT | |
| SCHEMBL3881940 | 0.59 | MAOB (0.65) | MAOBMAOAPOLBMAPTHSD17B10 | |
| SCHEMBL12694015 | 0.58 | SMN1; SMN2 (0.55) | MAOBALDH1A1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL8441466 | 0.58 | ESR2 (0.49) | ALDH1A1KDM4ESMN1; SMN2NPC1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5985912-A | COUMARONE COMPOUNDS AS BACTERICIDES | PFIZER INC. (US) | 1999-11-16 | — | — | US | disclosed |