Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | TNKS | O95271 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.38 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | PDE1A | P54750 | 1/20 | 0.38 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8440006 | 0.86 | ALDH1A1 (0.41) | ALDH1A1KDM4EHSD17B10LMNATP53 | |
| Hydrochloric Acid SCHEMBL8443235 | 0.85 | KDM4E (0.40) | ALDH1A1KDM4EHSD17B10LMNATP53 | |
| Hydrochloric Acid SCHEMBL8443238 | 0.84 | HTR2B (0.43) | ALDH1A1KDM4EHSD17B10LMNATP53 | |
| SCHEMBL8444336 | 0.80 | L3MBTL1 (0.44) | ALDH1A1KDM4EHSD17B10LMNATP53 | |
| Hydrochloric Acid SCHEMBL8440657 | 0.80 | KDM4E (0.42) | ALDH1A1KDM4EHSD17B10HPGDADORA1 | |
| SCHEMBL8440609 | 0.79 | HPGD (0.46) | ALDH1A1KDM4EHSD17B10LMNAHPGD | |
| SCHEMBL8442502 | 0.77 | FYN (0.42) | ALDH1A1KDM4EHSD17B10LMNATP53 | |
| SCHEMBL8576273 | 0.77 | TMEM97 (0.40) | ALDH1A1KDM4EHSD17B10LMNATP53 | |
| SCHEMBL8444471 | 0.76 | TNKS (0.49) | KDM4ECYP2D6TNKSCYP1A2KMT2A | |
| SCHEMBL8441352 | 0.75 | FYN (0.41) | ALDH1A1KDM4EHSD17B10LMNACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5968985-A | INHIBITORS OF SODIUM ION/HYDROGEN ION EXCHANGE IN CELLS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-10-19 | — | — | US | disclosed |
| EP-0773927-A2 | BENZOYLGUANIDINE DERIVATIVES AS MEDICAMENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-05-21 | — | — | EP | disclosed |
| WO-1996004241-A2 | BENZOYLGUANIDINE DERIVATIVES AS MEDICAMENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-02-15 | — | — | WO | disclosed |