Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 7/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.39 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.39 |
| ▸ | TOP2A | P11388 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | GRK5 | P34947 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | WNT1 | P04628 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8443248 | 0.87 | ROCK2 (0.41) | FYNALDH1A1CYP2D6LMNA | |
| SCHEMBL8441352 | 0.83 | FYN (0.41) | FYNKDM4EALDH1A1HSD17B10CYP2D6 | |
| SCHEMBL8440006 | 0.82 | ALDH1A1 (0.41) | KDM4EALDH1A1HSD17B10CYP2D6TOP2A | |
| SCHEMBL8442901 | 0.79 | NPC1 (0.46) | ALDH1A1GPR52 | |
| SCHEMBL8444336 | 0.79 | L3MBTL1 (0.44) | FYNKDM4EALDH1A1HSD17B10CYP2D6 | |
| SCHEMBL8444324 | 0.79 | USP2 (0.41) | FYNALDH1A1CAMK2DABL1USP2 | |
| Hydrochloric Acid SCHEMBL8440088 | 0.78 | ALDH1A1 (0.41) | FYNKDM4EALDH1A1HSD17B10CYP2D6 | |
| SCHEMBL8442844 | 0.77 | ALDH1A1 (0.43) | KDM4EALDH1A1HSD17B10CYP2D6TOP2A | |
| Hydrochloric Acid SCHEMBL8440657 | 0.76 | KDM4E (0.42) | FYNKDM4EALDH1A1HSD17B10TOP2A | |
| SCHEMBL8443415 | 0.75 | ALDH1A1 (0.46) | FYNKDM4EALDH1A1HSD17B10CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5968985-A | INHIBITORS OF SODIUM ION/HYDROGEN ION EXCHANGE IN CELLS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-10-19 | — | — | US | disclosed |
| EP-0773927-A2 | BENZOYLGUANIDINE DERIVATIVES AS MEDICAMENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-05-21 | — | — | EP | disclosed |
| WO-1996004241-A2 | BENZOYLGUANIDINE DERIVATIVES AS MEDICAMENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-02-15 | — | — | WO | disclosed |