Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
| ▸ | TNF | P01375 | 1/20 | 0.38 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.38 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1344772 | 0.79 | NPSR1 (0.50) | MAPTALDH1A1SMN1; SMN2KDM4ENPC1 | |
| SCHEMBL23504933 | 0.79 | NPSR1 (0.50) | MAPTALDH1A1SMN1; SMN2KDM4ENPC1 | |
| SCHEMBL8442853 | 0.79 | SMN1; SMN2 (0.41) | MAPTALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL1344768 | 0.79 | NPSR1 (0.50) | MAPTALDH1A1SMN1; SMN2KDM4ENPC1 | |
| SCHEMBL8848886 | 0.78 | PLA2G7 (0.47) | MAPTALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL8441573 | 0.78 | PLA2G7 (0.47) | MAPTALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL10085282 | 0.77 | MAPT (0.42) | MAPTALDH1A1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL11252094 | 0.75 | SMN1; SMN2 (0.41) | MAPTALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL11252091 | 0.75 | SMN1; SMN2 (0.41) | MAPTALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL16437274 | 0.74 | MAPT (0.47) | MAPTALDH1A1MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5965613-A | FUNGICIDES FOR USE IN AGRICULTURE AND HORTICULTURE; THE COMPOUNDS ALSO HAVE INSECTICIDAL AND ACARICIDAL ACTIVITY | NOVARTIS FINANCE CORPORATION (US) | 1999-10-12 | — | — | US | disclosed |