Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 12/20 | 0.48 |
| ▸ | PPARG | P37231 | 11/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | SGMS1 | Q86VZ5 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8441478 | 0.83 | ALDH1A1 (0.48) | ALDH1A1TP53GAAKDM4ESGMS1 | |
| SCHEMBL9773559 | 0.77 | ALDH1A1 (0.52) | ALDH1A1TP53GAAKDM4ETSHR | |
| SCHEMBL8559241 | 0.76 | ALDH1A1 (0.50) | PPARAPPARGALDH1A1KDM4ELMNA | |
| SCHEMBL8443300 | 0.76 | SGMS1 (0.53) | ALDH1A1TP53GAAKDM4ETSHR | |
| SCHEMBL8441480 | 0.74 | SGMS1 (0.56) | ALDH1A1TP53GAAKDM4ESGMS1 | |
| SCHEMBL8442525 | 0.73 | TBXA2R (0.52) | ALDH1A1KDM4ETSHRTDP1LMNA | |
| SCHEMBL8441161 | 0.73 | TBXA2R (0.52) | ALDH1A1TP53GAAKDM4ELMNA | |
| SCHEMBL7911840 | 0.72 | ALDH1A1 (0.62) | ALDH1A1GAAKDM4ETSHRLMNA | |
| SCHEMBL8440583 | 0.71 | ALDH1A1 (0.56) | ALDH1A1GAATSHRSGMS1LMNA | |
| SCHEMBL8442976 | 0.71 | ALDH1A1 (0.48) | ALDH1A1GAATSHRTDP1SGMS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5955505-A | TREATING NERVE DEGENERATIVE DISORDERS | NIPPON SUISAN KAISHA, LTD. (JP) | 1999-09-21 | — | — | US | disclosed |