Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | MMP2 | P08253 | 11/20 | 0.47 |
| ▸ | MMP13 | P45452 | 6/20 | 0.47 |
| ▸ | ADAMTS4 | O75173 | 2/20 | 0.47 |
| ▸ | MMP14 | P50281 | 2/20 | 0.47 |
| ▸ | ADAMTS5 | Q9UNA0 | 2/20 | 0.47 |
| ▸ | SGMS1 | Q86VZ5 | 1/20 | 0.45 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.45 |
| ▸ | MMP3 | P08254 | 4/20 | 0.44 |
| ▸ | MMP1 | P03956 | 4/20 | 0.44 |
| ▸ | MMP7 | P09237 | 3/20 | 0.44 |
| ▸ | MMP9 | P14780 | 3/20 | 0.44 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 4/20 | 0.43 |
| ▸ | CA1 | P00915 | 4/20 | 0.43 |
| ▸ | CA2 | P00918 | 4/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8442525 | 0.91 | TBXA2R (0.52) | ALDH1A1PKMMMP2MMP13ADAMTS4 | |
| SCHEMBL8440583 | 0.88 | ALDH1A1 (0.56) | ALDH1A1MEN1KMT2APKML3MBTL1 | |
| SCHEMBL8441478 | 0.88 | ALDH1A1 (0.48) | ALDH1A1MEN1KMT2AMMP2MMP13 | |
| SCHEMBL8437957 | 0.88 | MEN1 (0.54) | ALDH1A1MEN1KMT2AL3MBTL1TBXA2R | |
| SCHEMBL8440900 | 0.87 | ALDH1A1 (0.56) | ALDH1A1MEN1KMT2APKMMMP2 | |
| SCHEMBL8438766 | 0.85 | LMNA (0.53) | ALDH1A1MEN1KMT2APKML3MBTL1 | |
| SCHEMBL8437796 | 0.85 | ALDH1A1 (0.56) | ALDH1A1MEN1KMT2ATBXA2RGAA | |
| SCHEMBL8440909 | 0.81 | TBXAS1 (0.48) | TBXA2R | |
| SCHEMBL8441437 | 0.81 | TBXA2R (0.52) | ALDH1A1MEN1KMT2APKML3MBTL1 | |
| SCHEMBL8443153 | 0.81 | MEP1B (0.47) | ALDH1A1PKMMMP2MMP13ADAMTS4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5955505-A | TREATING NERVE DEGENERATIVE DISORDERS | NIPPON SUISAN KAISHA, LTD. (JP) | 1999-09-21 | — | — | US | disclosed |