Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | MMP2 | P08253 | 5/20 | 0.46 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.46 |
| ▸ | MMP13 | P45452 | 1/20 | 0.46 |
| ▸ | MMP14 | P50281 | 1/20 | 0.46 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.46 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 4/20 | 0.44 |
| ▸ | CA1 | P00915 | 4/20 | 0.44 |
| ▸ | CA2 | P00918 | 4/20 | 0.44 |
| ▸ | CA9 | Q16790 | 4/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8440583 | 0.91 | ALDH1A1 (0.56) | TBXA2RALDH1A1LMNAPKMSMN1; SMN2 | |
| SCHEMBL8437957 | 0.91 | MEN1 (0.54) | TBXA2RALDH1A1LMNATSHRNPSR1 | |
| SCHEMBL8441478 | 0.91 | ALDH1A1 (0.48) | TBXA2RALDH1A1KDM4EMMP2ADAMTS4 | |
| SCHEMBL8442976 | 0.91 | ALDH1A1 (0.48) | TBXA2RALDH1A1PKMTSHRTDP1 | |
| SCHEMBL8440900 | 0.90 | ALDH1A1 (0.56) | TBXA2RALDH1A1KDM4EPKMSMN1; SMN2 | |
| SCHEMBL8440909 | 0.89 | TBXAS1 (0.48) | TBXA2RTBXAS1 | |
| SCHEMBL8438766 | 0.88 | LMNA (0.53) | TBXA2RALDH1A1LMNAPKMSMN1; SMN2 | |
| SCHEMBL8437796 | 0.88 | ALDH1A1 (0.56) | TBXA2RALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL8443153 | 0.86 | MEP1B (0.47) | TBXA2RALDH1A1KDM4ELMNAPKM | |
| SCHEMBL8441001 | 0.85 | TBXA2R (0.38) | TBXA2RALDH1A1TSHRTDP1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5955505-A | TREATING NERVE DEGENERATIVE DISORDERS | NIPPON SUISAN KAISHA, LTD. (JP) | 1999-09-21 | — | — | US | disclosed |