Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | SGMS1 | Q86VZ5 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 3/20 | 0.44 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
| ▸ | MMP14 | P50281 | 1/20 | 0.44 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8442525 | 0.91 | TBXA2R (0.52) | ALDH1A1LMNAPKMSMN1; SMN2TSHR | |
| SCHEMBL8441478 | 0.88 | ALDH1A1 (0.48) | ALDH1A1GAAMEN1KMT2ASGMS1 | |
| SCHEMBL8437957 | 0.88 | MEN1 (0.54) | ALDH1A1GAALMNAMEN1KMT2A | |
| SCHEMBL8442976 | 0.88 | ALDH1A1 (0.48) | ALDH1A1GAAMEN1KMT2APKM | |
| SCHEMBL8440900 | 0.87 | ALDH1A1 (0.56) | ALDH1A1MEN1KMT2APKMSMN1; SMN2 | |
| SCHEMBL8438766 | 0.85 | LMNA (0.53) | ALDH1A1LMNAMEN1KMT2APKM | |
| SCHEMBL8437796 | 0.85 | ALDH1A1 (0.56) | ALDH1A1GAALMNAMEN1KMT2A | |
| SCHEMBL8441001 | 0.84 | TBXA2R (0.38) | ALDH1A1GAATSHRTBXA2RMMP2 | |
| SCHEMBL8440909 | 0.81 | TBXAS1 (0.48) | TBXA2R | |
| SCHEMBL8438050 | 0.81 | ALDH1A1 (0.59) | ALDH1A1GAATAAR1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5955505-A | TREATING NERVE DEGENERATIVE DISORDERS | NIPPON SUISAN KAISHA, LTD. (JP) | 1999-09-21 | — | — | US | disclosed |