SCHEMBL8443397

SCHEMBL8443397

CCOC(C)CCCCCc1ccc(-c2ncc(O)cn2)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 6/20 0.51
MAPT P10636 4/20 0.51
SMN1; SMN2 Q16637 3/20 0.51
KDM4E B2RXH2 3/20 0.51
ALDH1A1 P00352 3/20 0.51
MEN1 O00255 3/20 0.51
KMT2A Q03164 3/20 0.51
HSD17B10 Q99714 2/20 0.51
USP2 O75604 1/20 0.51
GAA P10253 1/20 0.51
HPGD P15428 1/20 0.51
RARB P10826 6/20 0.42
NPC1 O15118 4/20 0.40
STAT3 P40763 1/20 0.40
ATM Q13315 1/20 0.40
ESR1 P03372 2/20 0.38
ADRA2A P08913 2/20 0.38
ADORA3 P0DMS8 2/20 0.38
TACR2 P21452 2/20 0.38
SLC6A2 P23975 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8444589 0.83 RARB (0.44) RAB9AMAPTSMN1; SMN2KDM4EALDH1A1
SCHEMBL8052732 0.83 RAB9A (0.56) RAB9AMAPTSMN1; SMN2KDM4EALDH1A1
SCHEMBL8758438 0.80 RAB9A (0.58) RAB9AMAPTSMN1; SMN2KDM4EALDH1A1
SCHEMBL9098176 0.80 RAB9A (0.54) RAB9AMAPTSMN1; SMN2KDM4EALDH1A1
SCHEMBL8020482 0.80 ALDH1A1 (0.72) RAB9AMAPTSMN1; SMN2KDM4EALDH1A1
SCHEMBL9817420 0.80 ALDH1A1 (0.72) RAB9AMAPTSMN1; SMN2KDM4EALDH1A1
SCHEMBL9550608 0.80 ALDH1A1 (0.72) RAB9AMAPTSMN1; SMN2KDM4EALDH1A1
SCHEMBL6284665 0.80 ALDH1A1 (0.72) RAB9AMAPTSMN1; SMN2KDM4EALDH1A1
SCHEMBL8080064 0.80 ALDH1A1 (0.72) RAB9AMAPTSMN1; SMN2KDM4EALDH1A1
SCHEMBL8521888 0.79 RAB9A (0.43) RAB9AMAPTSMN1; SMN2KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0634469-B1 Compound having unsaturated side-chain, process for preparing the same, liquid crystalline polymer prepared from the same, liquid crystal mixture and display element SUMITOMO CHEMICAL CO (JP) 1999-10-06 EP disclosed
US-5662828-A Compound having unsaturated side chain, process for preparing the same, liquid crystalline polymer prepared from the same, liquid crystal mixture and display element SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-09-02 US disclosed
US-5554317-A POLYSILOXANE LIQUID CRYSTALLINE POLYMERS FORMED BY GRAFT POLYMERIZING AT LEAST ONE UNSATURATED COMPOUND WITH ONE OR MORE AROMATIC OR HETEROAROMATIC RINGS, OPTIONAL ETHER GROUP AND OPTIONAL ASYMMETRIC C ON POLYALKYLHYDROSILOXANE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-09-10 US disclosed
EP-0634469-A1 Compound having unsaturated side-chain, process for preparing the same, liquid crystalline polymer prepared from the same, liquid crystal mixture and display element SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1995-01-18 EP disclosed