Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 11/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8440322 | 0.87 | HTR1A (0.56) | HTR1ASLC6A4 | |
| SCHEMBL8440427 | 0.77 | HTR1A (0.43) | HTR1ASLC6A4ALDH1A1LMNACYP3A4 | |
| SCHEMBL8442339 | 0.76 | HTR1A (0.54) | HTR1AALDH1A1LMNACYP3A4ALOX12 | |
| SCHEMBL8443738 | 0.74 | HTR1A (0.53) | HTR1A | |
| SCHEMBL6964022 | 0.68 | HTR1A (1.00) | HTR1A | |
| SCHEMBL6964024 | 0.68 | HTR1A (1.00) | HTR1A | |
| SCHEMBL6976115 | 0.68 | HTR1A (1.00) | HTR1A | |
| SCHEMBL8544064 | 0.68 | HTR1A (0.51) | HTR1ASLC6A4 | |
| SCHEMBL9323906 | 0.67 | HTR1A (0.49) | HTR1ASLC6A4 | |
| SCHEMBL8443885 | 0.67 | HTR1A (0.41) | HTR1ASLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5958927-A | PSYCHOLOGICAL AND NERVOUS SYSTEM DISORDERS | ADIR ET COMPAGNIE (FR) | 1999-09-28 | — | — | US | disclosed |