Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.35 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CRHBP | P24387 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | CDK8 | P49336 | 1/20 | 0.30 |
| ▸ | CDK19 | Q9BWU1 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2877787 | 0.78 | MEN1 (0.33) | POLBALDH1A1KDM4EHSD17B10KMT2A | |
| SCHEMBL30764121 | 0.78 | MEN1 (0.30) | ALDH1A1KMT2AMEN1 | |
| SCHEMBL30764120 | 0.78 | MEN1 (0.30) | ALDH1A1KMT2AMEN1 | |
| SCHEMBL1258669 | 0.77 | HSP90AA1 (0.38) | HSP90AA1HSP90AB1LMNAPOLBALDH1A1 | |
| SCHEMBL601042 | 0.76 | HSP90AA1 (0.36) | HSP90AA1HSP90AB1LMNAPOLBALDH1A1 | |
| SCHEMBL97719 | 0.75 | — | — | |
| SCHEMBL31558754 | 0.74 | HSP90AA1 (0.59) | HSP90AA1HSP90AB1TRPV4POLBALDH1A1 | |
| SCHEMBL8539215 | 0.74 | HSP90AA1 (0.59) | HSP90AA1HSP90AB1TRPV4POLBALDH1A1 | |
| SCHEMBL6637012 | 0.74 | CA2 (0.47) | HSP90AA1HSP90AB1TRPV4ALDH1A1CYP3A4 | |
| SCHEMBL603692 | 0.74 | HSP90AA1 (0.44) | HSP90AA1HSP90AB1LMNAPOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 82 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117712479-B | Multifunctional fluorine-containing electrolyte additive and preparation method and application thereof | 山东森美越化工有限公司 | 2024-06-11 | — | — | CN | claimed |
| CN-117712479-A | Multifunctional fluorine-containing electrolyte additive and preparation method and application thereof | 山东森美越化工有限公司 | 2024-03-15 | — | — | CN | claimed |
| CN-111187220-B | Trifluoromethyl pyrimidine derivative containing Schiff base structural unit and preparation method and application thereof | 郑州大学 | 2022-08-02 | — | — | CN | claimed |
| CN-113046017-A | Insulating material for cable sealing and preparation method thereof | 浙江迪思威电气股份有限公司 | 2021-06-29 | — | — | CN | claimed |
| CN-109400988-B | Sealing gasket and preparation method thereof | 慈溪市春潮密封件有限公司 | 2020-09-25 | — | — | CN | claimed |
| CN-111187220-A | Trifluoromethyl pyrimidine derivative containing Schiff base structural unit and preparation method and application thereof | 郑州大学 | 2020-05-22 | — | — | CN | claimed |
| CN-115974850-B | Compound serving as AKR1C3 inhibitor as well as preparation method and application thereof | 中国药科大学 | 2024-08-06 | — | — | CN | disclosed |
| CN-117712479-B | Multifunctional fluorine-containing electrolyte additive and preparation method and application thereof | 山东森美越化工有限公司 | 2024-06-11 | — | — | CN | disclosed |
| US-11935803-B2 | Resin composition, laminate, semiconductor wafer with resin composition layer, substrate for mounting semiconductor with resin composition layer and semiconductor device | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2024-03-19 | — | — | US | disclosed |
| CN-117712479-A | Multifunctional fluorine-containing electrolyte additive and preparation method and application thereof | 山东森美越化工有限公司 | 2024-03-15 | — | — | CN | disclosed |
| CN-114644596-B | Fluoropyrimidine aromatic amine compound and application thereof | 青岛科技大学 | 2024-01-30 | — | — | CN | disclosed |
| CN-114605386-B | Fluorinated pyrimidine thioether aromatic ester insecticidal acaricide | 青岛科技大学 | 2023-12-12 | — | — | CN | disclosed |
| US-11725000-B2 | Apoptosis inhibitors | NATIONAL INSTITUTE OF BIOLOGICAL SCIENCES, BEIJING (CN) | 2023-08-15 | — | — | US | disclosed |
| EP-0533869-A1 | NEMATICIDAL PYRIMDINE DERIVATIVES | ZENECA LIMITED (GB) | 1993-03-31 | — | — | EP | disclosed |
| EP-0533870-A1 | NEMATOCIDE PYRIMIDINE DERIVATIVES | ZENECA LIMITED (GB) | 1993-03-31 | — | — | EP | disclosed |
| WO-1992017459-A1 | NEMATICIDAL PYRIMDINE DERIVATIVES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-10-15 | — | — | WO | disclosed |
| WO-1992017457-A1 | NEMATOCIDE PYRIMIDINE DERIVATIVES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-10-15 | — | — | WO | disclosed |
| EP-0506269-A1 | Nematicide pyrimidine derivatives | ZENECA LIMITED (GB) | 1992-09-30 | — | — | EP | disclosed |
| EP-0506270-A1 | Nematocide pyrimidine derivatives | ZENECA LIMITED (GB) | 1992-09-30 | — | — | EP | disclosed |
| EP-0395977-A1 | Process for the preparation of 4-hydroxy-6-polyfluoroalkylpyrimidines | LONZA AG (CH) | 1990-11-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11725000-B2 | Apoptosis inhibitors | BAX, SDHA, SDHB | HSP90AA1 544/4885HSP90AB1 254/4885TRPV4 2742/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.