Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | CTSV | O60911 | 2/20 | 0.46 |
| ▸ | CTSL | P07711 | 2/20 | 0.46 |
| ▸ | RXRA | P19793 | 1/20 | 0.46 |
| ▸ | PDE4A | P27815 | 1/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8052932 | 0.89 | SMN1; SMN2 (0.53) | PDE4DSMN1; SMN2NPC1HPGDRAB9A | |
| SCHEMBL11817706 | 0.84 | PDE4D (0.52) | PDE4DSMN1; SMN2NPC1HPGDRAB9A | |
| SCHEMBL10998628 | 0.84 | CTSV (0.49) | PDE4DSMN1; SMN2NPC1HPGDRAB9A | |
| SCHEMBL27967578 | 0.83 | PKM (0.58) | PDE4DSMN1; SMN2NPC1HPGDRAB9A | |
| SCHEMBL14882633 | 0.83 | CTSV (0.53) | PDE4DSMN1; SMN2NPC1HPGDRAB9A | |
| SCHEMBL27860093 | 0.80 | PDE4D (0.56) | PDE4DSMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL9729812 | 0.80 | LRRK2 (0.57) | SMN1; SMN2NPC1HPGDRAB9AMAPT | |
| SCHEMBL5467535 | 0.79 | PTGER1 (0.58) | SMN1; SMN2NPC1HPGDRAB9AMAPT | |
| SCHEMBL24379172 | 0.78 | CTSV (0.51) | SMN1; SMN2NPC1HPGDRAB9AMAPT | |
| SCHEMBL855207 | 0.78 | CTSV (0.54) | SMN1; SMN2NPC1HPGDRAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0915864-A1 | GASTROPROTECTIVE FLAVONE/FLAVANONE COMPOUNDS WITH THERAPEUTIC EFFECT ON INFLAMMATORY BOWEL DISEASE | Dong A Pharmaceutical Co. Ltd. (KR) | 1999-05-19 | — | — | EP | disclosed |
| WO-1998004541-A1 | GASTROPROTECTIVE FLAVONE/FLAVANONE COMPOUNDS WITH THERAPEUTIC EFFECT ON INFLAMMATORY BOWEL DISEASE | DONG A PHARMACEUTICAL CO., LTD. (KR) | 1998-02-05 | — | — | WO | disclosed |