Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | RXRA | P19793 | 1/20 | 0.44 |
| ▸ | CTSV | O60911 | 1/20 | 0.44 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8444239 | 0.89 | PDE4D (0.54) | SMN1; SMN2MAPTTDP1CYP2C9CYP2C19 | |
| SCHEMBL19267889 | 0.86 | SMN1; SMN2 (0.67) | SMN1; SMN2MAPTTDP1CYP2C9CYP2C19 | |
| SCHEMBL27954378 | 0.81 | MAPT (0.53) | SMN1; SMN2MAPTTDP1PDE4DHPGD | |
| SCHEMBL9729812 | 0.77 | LRRK2 (0.57) | SMN1; SMN2MAPTHPGDNPC1RAB9A | |
| SCHEMBL10998628 | 0.76 | CTSV (0.49) | SMN1; SMN2PDE4DHPGDNPC1RAB9A | |
| SCHEMBL11817706 | 0.76 | PDE4D (0.52) | SMN1; SMN2MAPTTDP1CYP2C9CYP2C19 | |
| SCHEMBL24708135 | 0.75 | SMN1; SMN2 (0.56) | SMN1; SMN2MAPTTDP1CYP2C9CYP2C19 | |
| SCHEMBL3679181 | 0.75 | SGMS2 (0.60) | SMN1; SMN2MAPTL3MBTL1NPC1LMNA | |
| SCHEMBL14882633 | 0.75 | CTSV (0.53) | SMN1; SMN2MAPTTDP1CYP2C9CYP2C19 | |
| SCHEMBL10928397 | 0.74 | L3MBTL1 (0.60) | SMN1; SMN2MAPTTDP1CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116768839-A | Synthesis method of oroxylin | 南京芩领医药科技有限公司 | 2023-09-19 | — | — | CN | disclosed |
| US-6025387-A | Gastroprotective flavone/flavanone compounds with therapeutic effect on inflammatory bowel disease | DONG A PHARMACEUTICAL CO., LTD. (KR) | 2000-02-15 | — | — | US | disclosed |