Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7873726 | 0.84 | NPC1 (0.41) | KMT2ASLC22A12MEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL7868598 | 0.82 | ALDH1A1 (0.44) | KMT2ASLC22A12MEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL10921467 | 0.80 | SSTR4 (0.43) | KMT2ASMN1; SMN2EPHX2NPC1RAB9A | |
| SCHEMBL18766090 | 0.78 | KIF11 (0.47) | KMT2AMEN1ALDH1A1EPHX2MAPT | |
| SCHEMBL8445850 | 0.78 | CES2 (0.42) | KMT2AMEN1ALDH1A1SMN1; SMN2EPHX2 | |
| SCHEMBL11360627 | 0.78 | SLC22A12 (0.45) | KMT2ASLC22A12MEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL15578056 | 0.75 | EPHX2 (0.45) | SLC22A12EPHX2 | |
| SCHEMBL8446830 | 0.75 | NPC1 (0.48) | KMT2AMEN1ALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL15578171 | 0.74 | ACACB (0.45) | ALDH1A1SMN1; SMN2NPC1LMNAMAPT | |
| SCHEMBL22772342 | 0.73 | ESR1 (0.48) | KMT2AMEN1ALDH1A1THRBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0618907-B1 | 1-(ARYLALKYL-AMINOALKYL)IMIDAZOLE DERIVATIVES, PROCESSES OF PREPARATION AND USE AS THERAPEUTICAL AGENTS | BRITISH TECH GROUP INT (GB) | 1999-04-28 | — | — | EP | disclosed |