Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS | O95271 | 1/20 | 0.44 |
| ▸ | TTR | P02766 | 4/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.40 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.40 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.40 |
| ▸ | DHODH | Q02127 | 2/20 | 0.38 |
| ▸ | NQO1 | P15559 | 1/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | EYA3 | Q99504 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8444010 | 0.91 | TNKS (0.45) | TNKSTTRPTPN1KDM4EMAPT | |
| SCHEMBL8441434 | 0.82 | TTR (0.48) | TNKSTTRPTPN1KDM4EUSP2 | |
| SCHEMBL8442828 | 0.77 | TNKS (0.46) | TNKSKDM4EMAPTCA1CA2 | |
| SCHEMBL29644549 | 0.73 | DHODH (0.53) | KDM4EDHODHMAPT | |
| SCHEMBL10009333 | 0.73 | DHODH (0.53) | KDM4EDHODHMAPT | |
| SCHEMBL8440006 | 0.73 | ALDH1A1 (0.41) | TNKSKDM4E | |
| SCHEMBL8441247 | 0.69 | FABP4 (0.38) | TTRPTPN1KDM4EDHODH | |
| SCHEMBL29018195 | 0.68 | CA1 (0.46) | TNKSPTPN1KDM4EPTGS1MAPT | |
| SCHEMBL8442687 | 0.68 | CYP2C19 (0.50) | TNKSTTRPTPN1KDM4EMAPT | |
| SCHEMBL11637449 | 0.68 | KMO (0.50) | TNKSTTRPTPN1KDM4EUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5968985-A | INHIBITORS OF SODIUM ION/HYDROGEN ION EXCHANGE IN CELLS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-10-19 | — | — | US | disclosed |
| US-5951913-A | Liquid crystal compositions comprising silacyclohexane compounds | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1999-09-14 | — | — | US | disclosed |
| EP-0773927-A2 | BENZOYLGUANIDINE DERIVATIVES AS MEDICAMENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-05-21 | — | — | EP | disclosed |
| WO-1996004241-A2 | BENZOYLGUANIDINE DERIVATIVES AS MEDICAMENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-02-15 | — | — | WO | disclosed |