Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.60 |
| ▸ | CA1 | P00915 | 2/20 | 0.60 |
| ▸ | CA2 | P00918 | 2/20 | 0.60 |
| ▸ | CA9 | Q16790 | 2/20 | 0.60 |
| ▸ | ERN1 | O75460 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | ASH1L | Q9NR48 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | AXL | P30530 | 1/20 | 0.43 |
| ▸ | SDHB | P21912 | 1/20 | 0.42 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7815828 | 0.81 | HSD17B10 (0.48) | CA12CA1CA2CA9ERN1 | |
| SCHEMBL8444035 | 0.80 | ERN1 (0.56) | CA12CA1CA2CA9ERN1 | |
| SCHEMBL8444332 | 0.80 | CA12 (0.47) | CA12CA1CA2CA9ERN1 | |
| SCHEMBL8804542 | 0.79 | F10 (0.41) | CA12CA1CA2CA9 | |
| SCHEMBL8439989 | 0.78 | PKM (0.49) | CA12CA1CA2CA9ERN1 | |
| SCHEMBL8444039 | 0.78 | F10 (0.39) | CA12CA1CA2CA9 | |
| SCHEMBL8804547 | 0.78 | HTR2B (0.43) | — | |
| SCHEMBL8444041 | 0.77 | CA12 (0.37) | CA12CA1CA2CA9 | |
| SCHEMBL16749656 | 0.76 | CA12 (0.58) | CA12CA1CA2CA9ERN1 | |
| SCHEMBL8442500 | 0.76 | CA2 (0.64) | CA12CA1CA2CA9ERN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5968985-A | INHIBITORS OF SODIUM ION/HYDROGEN ION EXCHANGE IN CELLS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-10-19 | — | — | US | disclosed |