Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.78 |
| ▸ | MEN1 | O00255 | 2/20 | 0.78 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.78 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.78 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.78 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.78 |
| ▸ | HPGD | P15428 | 1/20 | 0.78 |
| ▸ | HTT | P42858 | 1/20 | 0.78 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | RPS6KB1 | P23443 | 10/20 | 0.40 |
| ▸ | AURKA | O14965 | 9/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7142147 | 0.87 | MAPT (1.00) | MAPTMEN1KMT2AKDM4EHSP90AA1 | |
| SCHEMBL30919368 | 0.87 | MAPT (1.00) | MAPTMEN1KMT2AKDM4EHSP90AA1 | |
| SCHEMBL29356341 | 0.77 | MAPT (0.63) | MAPTMEN1KMT2AKDM4EHSP90AA1 | |
| SCHEMBL16323481 | 0.77 | MAPT (0.63) | MAPTMEN1KMT2AKDM4EHSP90AA1 | |
| SCHEMBL20869701 | 0.74 | MAPT (0.60) | MAPTMEN1KMT2AKDM4EHSP90AA1 | |
| SCHEMBL7820954 | 0.74 | KMT2A (0.71) | MAPTMEN1KMT2AKDM4EHSP90AA1 | |
| SCHEMBL14200890 | 0.73 | MAPT (0.46) | MAPTMEN1KMT2AKDM4EHSP90AA1 | |
| SCHEMBL460367 | 0.69 | MAOA (0.56) | MAPTMEN1KMT2AKDM4EHSP90AA1 | |
| SCHEMBL6464966 | 0.68 | ATM (0.61) | KDM4EKEAP1NFE2L2ALDH1A1GRK6 | |
| SCHEMBL8941899 | 0.65 | MAPT (0.76) | MAPTMEN1KMT2AKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5861398-A | Benzoperimidine-carboxylic acids and derivatives thereof | ALANEX CORPORATION (US) | 1999-01-19 | — | — | US | disclosed |
| WO-1998008821-A1 | BENZOPERIMIDINE-CARBOXYLIC ACIDS AND DERIVATIVES THEREOF | AGOURON ACQUISITION CORP. (US) | 1998-03-05 | — | — | WO | disclosed |