Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDE | P14735 | 2/20 | 0.46 |
| ▸ | APAF1 | O14727 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 3/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.34 |
| ▸ | UBE2N | P61088 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8442413 | 0.94 | APAF1 (0.45) | IDEAPAF1ATMCYP2D6SLC6A2 | |
| SCHEMBL8443523 | 0.94 | APAF1 (0.45) | IDEAPAF1ATMCYP2D6SLC6A2 | |
| SCHEMBL8445200 | 0.86 | KDM4E (0.37) | NPSR1HPGDKDM4EALDH1A1HSD17B10 | |
| SCHEMBL8442954 | 0.80 | DRD2 (0.36) | NPSR1HPGDKDM4EALDH1A1HSD17B10 | |
| SCHEMBL8445196 | 0.78 | SCN7A (0.43) | CYP2D6NPSR1HPGDKDM4EALDH1A1 | |
| SCHEMBL8442952 | 0.73 | TMEM97 (0.44) | — | |
| SCHEMBL8445198 | 0.73 | OPRM1 (0.47) | NPSR1KDM4EALDH1A1HSD17B10SCN7A | |
| SCHEMBL8446025 | 0.72 | GRIN1 (0.48) | IDEAPAF1ATM | |
| SCHEMBL28404370 | 0.71 | KDM4E (0.59) | NPSR1HPGDKDM4EALDH1A1HSD17B10 | |
| SCHEMBL30259518 | 0.71 | APAF1 (0.53) | IDEAPAF1ATMCYP2D6SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934932-A1 | QUINOLINE DERIVATIVES AND PSYCHOTROPIC AGENT | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1999-08-11 | — | — | EP | claimed |
| EP-0934932-A1 | QUINOLINE DERIVATIVES AND PSYCHOTROPIC AGENT | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1999-08-11 | — | — | EP | disclosed |