Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 10/20 | 0.62 |
| ▸ | CTSB | P07858 | 8/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8445299 | 0.90 | CTSL (0.66) | CTSLCTSBGAA | |
| SCHEMBL8445281 | 0.87 | CTSL (0.60) | CTSLCTSBGAA | |
| SCHEMBL8445288 | 0.86 | CTSL (0.82) | CTSLCTSB | |
| SCHEMBL8445297 | 0.84 | CTSL (0.68) | CTSLCTSB | |
| SCHEMBL8445287 | 0.83 | CTSL (0.58) | CTSLCTSBGAA | |
| SCHEMBL942218 | 0.81 | GAA (0.73) | CTSLCTSBGAA | |
| SCHEMBL1198420 | 0.72 | CES2 (0.60) | CTSLCTSBGAA | |
| SCHEMBL10672352 | 0.70 | CES2 (0.62) | CTSLGAA | |
| SCHEMBL8445279 | 0.69 | CTSL (0.65) | CTSLCTSB | |
| SCHEMBL2674247 | 0.69 | CTSL (0.69) | CTSLCTSBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040014801-A1 | Thio semicarbazone and semicarbazone inhibitors of cysteine proteases and methods of their use | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2004-01-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040014801-A1 | Thio semicarbazone and semicarbazone inhibitors of cysteine proteases and methods of their use | CTSB, CTSS, CTSL | CTSL 3/4885CTSB 1/4885GAA 470/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.