Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 18/20 | 0.67 |
| ▸ | CHRM4 | P08173 | 18/20 | 0.67 |
| ▸ | CHRM5 | P08912 | 18/20 | 0.67 |
| ▸ | CHRM1 | P11229 | 18/20 | 0.67 |
| ▸ | CHRM3 | P20309 | 18/20 | 0.67 |
| ▸ | DRD2 | P14416 | 14/20 | 0.63 |
| ▸ | DRD4 | P21917 | 14/20 | 0.63 |
| ▸ | DRD3 | P35462 | 14/20 | 0.63 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.63 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.63 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.63 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.63 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.63 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.52 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8445224 | 0.80 | CHRM1 (0.74) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL29400334 | 0.77 | CHRM2 (1.00) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL4100746 | 0.77 | CHRM2 (1.00) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL8442782 | 0.77 | CHRM2 (0.69) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL27074530 | 0.76 | CHRM1 (0.98) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL8443011 | 0.76 | CHRM1 (0.68) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL8445380 | 0.76 | CHRM2 (0.68) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL8443141 | 0.76 | CHRM2 (0.68) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL8445400 | 0.76 | CHRM2 (0.62) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL7826648 | 0.76 | HTR2C (0.47) | CHRM2CHRM4CHRM5CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934932-A1 | QUINOLINE DERIVATIVES AND PSYCHOTROPIC AGENT | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1999-08-11 | — | — | EP | disclosed |