Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 14/20 | 0.62 |
| ▸ | CHRM4 | P08173 | 14/20 | 0.62 |
| ▸ | CHRM5 | P08912 | 14/20 | 0.62 |
| ▸ | CHRM1 | P11229 | 14/20 | 0.62 |
| ▸ | CHRM3 | P20309 | 14/20 | 0.62 |
| ▸ | DRD2 | P14416 | 12/20 | 0.61 |
| ▸ | DRD4 | P21917 | 12/20 | 0.61 |
| ▸ | DRD3 | P35462 | 12/20 | 0.61 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.61 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.61 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.61 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.61 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.61 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6953531 | 0.80 | ACHE (0.55) | GPR119KDM4EPKM | |
| SCHEMBL5870656 | 0.80 | KDM1A (0.51) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL7479526 | 0.79 | — | — | |
| SCHEMBL5475624 | 0.78 | ACHE (0.53) | GPR119KDM4EPKM | |
| SCHEMBL31596884 | 0.78 | GPR119 (0.53) | GPR119KDM4EPKM | |
| SCHEMBL24664329 | 0.77 | KDM4E (0.60) | GPR119KDM4EPKM | |
| SCHEMBL31033157 | 0.76 | DRD2 (0.47) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL8445319 | 0.76 | CHRM2 (0.67) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL4100746 | 0.76 | CHRM2 (1.00) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL30987427 | 0.76 | DRD2 (0.53) | CHRM2CHRM4CHRM5CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934932-A1 | QUINOLINE DERIVATIVES AND PSYCHOTROPIC AGENT | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1999-08-11 | — | — | EP | disclosed |