Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | TKT | P29401 | 5/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL479344 | 0.98 | LMNA (0.61) | LMNATKTHSP90AA1KDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL6520994 | 0.96 | LMNA (0.59) | LMNATKTHSP90AA1KDM4EALDH1A1 | |
| Phosphoric Acid SCHEMBL851329 | 0.89 | LMNA (0.53) | LMNATKTHSP90AA1 | |
| Phosphoric Acid SCHEMBL1533803 | 0.89 | LMNA (0.53) | LMNATKTHSP90AA1 | |
| Pyrophosphoric Acid SCHEMBL851327 | 0.84 | LMNA (0.51) | LMNATKT | |
| Pyrazole SCHEMBL4017447 | 0.80 | LMNA (0.48) | LMNATKTHSP90AA1KDM4E | |
| SCHEMBL23748348 | 0.79 | LMNA (0.63) | LMNATKTHSP90AA1KDM4EALDH1A1 | |
| SCHEMBL12346332 | 0.79 | LMNA (0.63) | LMNATKTKDM4EALDH1A1 | |
| SCHEMBL29895545 | 0.79 | LMNA (0.63) | LMNATKTHSP90AA1KDM4EALDH1A1 | |
| SCHEMBL478879 | 0.79 | LMNA (0.63) | LMNATKTHSP90AA1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5958387-A | COPOLYMER OF SILOXANE AND HYDROLYZED OR UNHYDROLYZED PROTEIN, OR DIMETHICONE COPOLYOLS AND THEIR DERIVATIVES SOLUBILIZED IN AQUEOUS PHASE | L'OREAL (FR) | 1999-09-28 | — | — | US | disclosed |
| US-5626853-A | Aqueous make-up gel containing organopolysiloxane | L'OREAL (FR) | 1997-05-06 | — | — | US | disclosed |