Pyrophosphoric Acid

Pyrophosphoric Acid

SCHEMBL851327

Cc1ncc(CO)c(N)n1.O=P(O)(O)OP(=O)(O)O

nearest known ligand 0.54

Full drug profile on Sugi Atlas →

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.51
TKT P29401 7/20 0.49
TDP1 Q9NUW8 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phosphoric Acid SCHEMBL851329 0.91 LMNA (0.53) LMNATKTTDP1
Phosphoric Acid SCHEMBL1533803 0.91 LMNA (0.53) LMNATKTTDP1
SCHEMBL479344 0.85 LMNA (0.61) LMNATKT
SCHEMBL5916304 0.84 LMNA (0.50) LMNATKTTDP1
SCHEMBL8445448 0.84 LMNA (0.59) LMNATKT
Hydrochloric Acid SCHEMBL6520994 0.84 LMNA (0.59) LMNATKT
Pyrophosphoric Acid SCHEMBL5922584 0.81 TDP1 (0.58) LMNATKTTDP1
SCHEMBL851328 0.81 LMNA (0.57) LMNATKTTDP1
SCHEMBL3371360 0.80 LMNA (0.61) LMNATKTTDP1
SCHEMBL849877 0.78 LMNA (0.53) LMNATKTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260022411-A1 MICROBIAL CELL FACTORIES PRODUCING THIAMINE BIOSYNTIA APS (DK) 2026-01-22 US claimed
EP-4555076-A1 MICROBIAL CELL FACTORIES PRODUCING THIAMINE Biosyntia ApS (DK) 2025-05-21 EP claimed
CN-119731312-A Microbial cell factory for producing thiamine 拜奥信尼亚私营有限责任公司 2025-03-28 CN claimed
US-20240368659-A1 MICROBIAL CELL FACTORIES PRODUCING VITAMIN B COMPOUNDS BIOSYNTIA APS (DK) 2024-11-07 US claimed
EP-4370653-A2 MICROBIAL CELL FACTORIES PRODUCING VITAMIN B COMPOUNDS Biosyntia ApS (DK) 2024-05-22 EP claimed
CN-117897476-A Microbial cell factory for producing vitamin B compounds 拜奥信尼亚私营有限责任公司 2024-04-16 CN claimed
WO-2024013212-A1 MICROBIAL CELL FACTORIES PRODUCING THIAMINE BIOSYNTIA APS (DK) 2024-01-18 WO claimed
WO-2023285585-A2 MICROBIAL CELL FACTORIES PRODUCING VITAMIN B COMPOUNDS BIOSYNTIA APS (DK) 2023-01-19 WO claimed
US-20040006040-A1 Method for the identification and treatment of pathogenic microorganism infections by inhibiting one or more enzymes in an essential metabolic pathway and compounds and pharmaceutical compositions useful therefor PYRO PHARMACEUTICALS, INC. 2004-01-08 US claimed
EP-1093520-A1 HMP-P KINASE AND TMP-PPASE FROM ARABIDOPSIS THALIANA AND THEIR USE IN HERBICIDE SCREENING Syngenta Participations AG (CH) 2001-04-25 EP claimed
WO-2000000623-A1 HMP-P KINASE AND TMP-PPASE FROM ARABIDOPSIS THALIANA AND THEIR USE IN HERBICIDE SCREENING SYNGENTA PARTICIPATIONS AG (CH) 2000-01-06 WO claimed
US-20260022411-A1 MICROBIAL CELL FACTORIES PRODUCING THIAMINE BIOSYNTIA APS (DK) 2026-01-22 US disclosed
EP-4555076-A1 MICROBIAL CELL FACTORIES PRODUCING THIAMINE Biosyntia ApS (DK) 2025-05-21 EP disclosed
CN-119731312-A Microbial cell factory for producing thiamine 拜奥信尼亚私营有限责任公司 2025-03-28 CN disclosed
US-20240376480-A1 TREATMENT OF ELEVATED METABOLITE LEVELS USING NANOCARRIERS RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) 2024-11-14 US disclosed
US-20030180830-A1 Method for the identification and treatment of pathogenic microorganism infections by inhibiting one or more enzymes in an essential metabolic pathway PYRO PHARMACEUTICALS, INC. 2003-09-25 US disclosed
WO-2003036296-A1 COMPOSITIONS AND METHODS FOR MODELING SACCHAROMYCES CEREVISIAE METABOLISM THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2003-05-01 WO disclosed
EP-1093520-A1 HMP-P KINASE AND TMP-PPASE FROM ARABIDOPSIS THALIANA AND THEIR USE IN HERBICIDE SCREENING Syngenta Participations AG (CH) 2001-04-25 EP disclosed
EP-1059354-A2 Sequence-determined DNA fragments and corresponding polypeptides encoded thereby Ceres Incorporated (US) 2000-12-13 EP disclosed
WO-2000000623-A1 HMP-P KINASE AND TMP-PPASE FROM ARABIDOPSIS THALIANA AND THEIR USE IN HERBICIDE SCREENING SYNGENTA PARTICIPATIONS AG (CH) 2000-01-06 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040006040-A1 Method for the identification and treatment of pathogenic microorganism infections by inhibiting one or more enzymes in an essential metabolic pathway and compounds and pharmaceutical compositions useful therefor CYP51A1, ME1, BPGM LMNA 3872/4885TKT 24/4885TDP1 3936/4885
US-20260022411-A1 MICROBIAL CELL FACTORIES PRODUCING THIAMINE AHCY, SHMT1, MTHFD1 LMNA 4260/4885TKT 22/4885TDP1 1224/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.