Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 2/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.40 |
| ▸ | FAAH | O00519 | 9/20 | 0.39 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1798902 | 0.91 | HTR6 (0.41) | HTR6GPR119FAAHTGFBR1 | |
| SCHEMBL8174907 | 0.86 | HTR6 (0.39) | HTR6 | |
| SCHEMBL1801756 | 0.80 | HTR6 (0.41) | HTR6GPR119USP30TGFBR1 | |
| SCHEMBL8177018 | 0.80 | CPT1A (0.41) | HTR6USP30 | |
| SCHEMBL1800049 | 0.77 | HTR6 (0.39) | HTR6 | |
| SCHEMBL3346600 | 0.75 | HTR6 (0.38) | HTR6FAAHMAPT | |
| SCHEMBL8478692 | 0.75 | CDK5 (0.41) | HTR6KDM4EMAPT | |
| SCHEMBL8168890 | 0.75 | HTR6 (0.40) | HTR6FAAHMAPT | |
| SCHEMBL14049072 | 0.74 | HTR6 (0.40) | HTR6 | |
| SCHEMBL13539079 | 0.74 | BRD4 (0.37) | HTR6MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1749829-A1 | JNK inhibitors | Eisai London Research Laboratories Limited (GB) | 2007-02-07 | — | — | EP | disclosed |