Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPSAB1 | Q15661 | 3/20 | 0.40 |
| ▸ | TPSD1 | Q9BZJ3 | 3/20 | 0.40 |
| ▸ | TPSG1 | Q9NRR2 | 3/20 | 0.40 |
| ▸ | F2 | P00734 | 3/20 | 0.40 |
| ▸ | PLG | P00747 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.35 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8444889 | 1.00 | TPSAB1 (0.40) | TPSAB1TPSD1TPSG1F2PLG | |
| SCHEMBL8449023 | 0.90 | TPSAB1 (0.40) | TPSAB1TPSD1TPSG1F2PLG | |
| SCHEMBL8447158 | 0.90 | TPSAB1 (0.39) | TPSAB1TPSD1TPSG1F2PLG | |
| SCHEMBL8440441 | 0.87 | HSD11B1 (0.35) | DPP8DPP9ALDH1A1MAPT | |
| SCHEMBL8436695 | 0.87 | HSD11B1 (0.35) | DPP8DPP9ALDH1A1MAPT | |
| SCHEMBL8449288 | 0.85 | CCR5 (0.35) | TPSAB1TPSD1TPSG1F2PLG | |
| SCHEMBL8444911 | 0.85 | GAA (0.41) | TPSAB1TPSD1TPSG1F2PLG | |
| SCHEMBL8448646 | 0.85 | GAA (0.41) | TPSAB1TPSD1TPSG1F2PLG | |
| SCHEMBL8447430 | 0.85 | TPSAB1 (0.39) | TPSAB1TPSD1TPSG1F2PLG | |
| SCHEMBL8444908 | 0.85 | TPSAB1 (0.39) | TPSAB1TPSD1TPSG1F2PLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5977097-A | 1-methylcarbapenem derivatives | SANKYO COMPANY LIMITED (JP) | 1999-11-02 | — | — | US | disclosed |
| EP-0900797-A1 | 1-METHYLCARBAPENEM DERIVATIVES | SANKYO COMPANY LIMITED (JP) | 1999-03-10 | — | — | EP | disclosed |