Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 3/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | NR1D1 | P20393 | 3/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.34 |
| ▸ | NR1D2 | Q14995 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | PLG | P00747 | 1/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.33 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.33 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.33 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.33 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.33 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.33 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8449100 | 0.91 | ALDH1A1 (0.35) | CCR5NR1D1NR1H3NR1D2ALDH1A1 | |
| SCHEMBL8444872 | 0.91 | ALDH1A1 (0.35) | CCR5NR1D1NR1H3NR1D2ALDH1A1 | |
| SCHEMBL7450103 | 0.89 | GRIN2B (0.37) | CCR5GRIN2BNR1D1NR1H3NR1D2 | |
| SCHEMBL8447213 | 0.89 | GRIN2B (0.37) | CCR5GRIN2BNR1D1NR1H3NR1D2 | |
| SCHEMBL8444889 | 0.85 | TPSAB1 (0.40) | GRIN2BALDH1A1MAPTF2PLG | |
| SCHEMBL8445887 | 0.85 | TPSAB1 (0.40) | GRIN2BALDH1A1MAPTF2PLG | |
| SCHEMBL8449152 | 0.84 | CCR5 (0.36) | CCR5GRIN2BNR1D1NR1H3NR1D2 | |
| SCHEMBL8444881 | 0.84 | GRIN2B (0.36) | CCR5GRIN2BNR1D1NR1H3NR1D2 | |
| SCHEMBL8436695 | 0.84 | HSD11B1 (0.35) | ALDH1A1MAPTDPP8DPP9 | |
| SCHEMBL8444892 | 0.84 | CCR5 (0.40) | CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5977097-A | 1-methylcarbapenem derivatives | SANKYO COMPANY LIMITED (JP) | 1999-11-02 | — | — | US | disclosed |
| EP-0900797-A1 | 1-METHYLCARBAPENEM DERIVATIVES | SANKYO COMPANY LIMITED (JP) | 1999-03-10 | — | — | EP | disclosed |