Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.43 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.41 |
| ▸ | PLAU | P00749 | 1/20 | 0.41 |
| ▸ | NOS3 | P29474 | 2/20 | 0.41 |
| ▸ | NOS1 | P29475 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | TPH1 | P17752 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8445406 | 0.98 | PKM (0.44) | PKMSLC9A1HSD17B1PLAUNOS3 | |
| SCHEMBL8446223 | 0.87 | HTR2B (0.45) | SLC9A1TPH1 | |
| SCHEMBL322274 | 0.80 | PKM (0.52) | PKMHSD17B1NOS3NOS1HTT | |
| SCHEMBL29803190 | 0.80 | PKM (0.52) | PKMHSD17B1NOS3NOS1HTT | |
| SCHEMBL7295677 | 0.78 | PKM (0.57) | PKMHSD17B1HTTPOLB | |
| SCHEMBL14265179 | 0.76 | TPH1 (0.56) | SLC9A1NOS3NOS1TPH1 | |
| SCHEMBL29955411 | 0.74 | CSNK2A1 (0.59) | PKMHTTCA1CA2 | |
| SCHEMBL458033 | 0.74 | CSNK2A1 (0.59) | PKMHTTCA1CA2 | |
| SCHEMBL3183606 | 0.73 | PKM (0.52) | PKMHSD17B1HTTCA1CA2 | |
| Hydrochloric Acid SCHEMBL8643344 | 0.72 | HTR2B (0.50) | SLC9A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0628543-B1 | Substituted benzoylguanidines, process for their preparation, their use as medicament or diagnostic agent, as well as a medicament containing them | HOECHST AG (DE) | 1999-06-16 | — | — | EP | claimed |