Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.64 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.63 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8949449 | 0.81 | ALDH1A1 (0.56) | ALDH1A1GAAMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL8648272 | 0.81 | GAA (0.54) | ALDH1A1TBXAS1GAAMAPTTSHR | |
| Hydrochloric Acid SCHEMBL8949432 | 0.81 | ALDH1A1 (0.55) | ALDH1A1GAAMAPTTSHRKDM4E | |
| SCHEMBL7879569 | 0.81 | QPCT (0.49) | ALDH1A1MAPTTSHRSMN1; SMN2NPC1 | |
| SCHEMBL8447070 | 0.80 | TBXAS1 (0.55) | ALDH1A1TBXAS1GAAMAPTTSHR | |
| SCHEMBL8444586 | 0.79 | ALDH1A1 (0.64) | ALDH1A1TBXAS1GAAMAPTTSHR | |
| SCHEMBL8949297 | 0.78 | SMN1; SMN2 (0.52) | ALDH1A1GAAMAPTTSHRHTT | |
| SCHEMBL7879609 | 0.78 | GAA (0.53) | ALDH1A1GAAMAPTTSHRHTT | |
| SCHEMBL8443962 | 0.78 | LMNA (0.56) | ALDH1A1SMN1; SMN2MEN1KMT2APOLB | |
| SCHEMBL7875046 | 0.78 | LMNA (0.57) | ALDH1A1TBXAS1GAAMAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0618907-B1 | 1-(ARYLALKYL-AMINOALKYL)IMIDAZOLE DERIVATIVES, PROCESSES OF PREPARATION AND USE AS THERAPEUTICAL AGENTS | BRITISH TECH GROUP INT (GB) | 1999-04-28 | — | — | EP | disclosed |
| US-5547972-A | 1-(ARLALKYLAMINOALKYL) IMIDAZOLE DERIVATIVES | THE BOOTS COMPANY PLC (GB) | 1996-08-20 | — | — | US | disclosed |
| WO-1993013075-A1 | 1-(ARYLALKYL-AMINOALKYL)IMIDAZOLE DERIVATIVES, PROCESSES OF PREPARATION AND USE AS THERAPEUTICAL AGENTS | THE BOOTS COMPANY PLC (GB) | 1993-07-08 | — | — | WO | disclosed |