Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | ADAMTS4 | O75173 | 4/20 | 0.42 |
| ▸ | MMP9 | P14780 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 2/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
| ▸ | MMP7 | P09237 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8445988 | 0.86 | L3MBTL1 (0.37) | ADAMTS4MMP9LMNAHTTL3MBTL1 | |
| SCHEMBL8447163 | 0.84 | NPSR1 (0.41) | MAPTNPSR1ADAMTS4MMP9ALDH1A1 | |
| SCHEMBL8070495 | 0.79 | KDM4E (0.67) | MAPTKDM4EALDH1A1LMNAHTT | |
| SCHEMBL8447165 | 0.77 | NPSR1 (0.45) | NPSR1ADAMTS4MMP9ALDH1A1LMNA | |
| SCHEMBL7995261 | 0.76 | TTR (0.61) | NPSR1ALDH1A1POLB | |
| SCHEMBL8059681 | 0.75 | TTR (0.45) | MAPTNPSR1L3MBTL1POLBSMN1; SMN2 | |
| SCHEMBL8073502 | 0.75 | TTR (0.51) | MAPTNPSR1ALDH1A1L3MBTL1POLB | |
| SCHEMBL8059678 | 0.74 | NPSR1 (0.44) | NPSR1ADAMTS4ALDH1A1LMNAL3MBTL1 | |
| SCHEMBL8059524 | 0.74 | KDM4E (0.50) | MAPTKDM4EALDH1A1LMNAHTT | |
| SCHEMBL8070492 | 0.74 | PKM (0.46) | MAPTKDM4ENPSR1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0723956-B1 | Basically substituted benzoylguanidines, process for their preparation, their use as medicaments or diagnostics as well as medicaments containing them | HOECHST AG (DE) | 1999-10-13 | — | — | EP | disclosed |
| EP-0723956-A1 | Basically substituted benzoylguanidines, process for their preparation, their use as medicaments or diagnostics as well as medicaments containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-07-31 | — | — | EP | disclosed |