Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN8A | Q9UQD0 | 2/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | HTR1D | P28221 | 1/20 | 0.35 |
| ▸ | HTR1B | P28222 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | HTR5A | P47898 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.35 |
| ▸ | CRHR1 | P34998 | 5/20 | 0.34 |
| ▸ | RAD52 | P43351 | 1/20 | 0.33 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8444362 | 0.98 | RAD52 (0.36) | SCN8ACHRM2CYP3A4HPGDALDH1A1 | |
| SCHEMBL13330470 | 0.77 | MEN1 (0.49) | CHRM2ALDH1A1HTR1AHTR1DHTR1B | |
| SCHEMBL13067432 | 0.73 | ALDH1A1 (0.48) | CYP3A4HPGDALDH1A1 | |
| SCHEMBL19657536 | 0.72 | SLC6A4 (0.42) | SCN8ACHRM2CYP3A4HTR1B | |
| SCHEMBL15865628 | 0.71 | APLNR (0.48) | ALDH1A1HTR2AHTR2C | |
| SCHEMBL25471395 | 0.70 | HTR2A (0.47) | CHRM2ALDH1A1HTR1AHTR1DHTR1B | |
| SCHEMBL13114968 | 0.70 | CD274 (0.48) | HTR1AHTR1DHTR1BHTR2AHTR2C | |
| Formic Acid SCHEMBL6324510 | 0.70 | MEN1 (0.50) | CHRM2ALDH1A1 | |
| SCHEMBL4030406 | 0.69 | CHRM2 (0.70) | SCN8ACHRM2ALDH1A1HTR2ARAD52 | |
| SCHEMBL3264888 | 0.68 | APLNR (0.50) | SCN8ACHRM2HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0618907-B1 | 1-(ARYLALKYL-AMINOALKYL)IMIDAZOLE DERIVATIVES, PROCESSES OF PREPARATION AND USE AS THERAPEUTICAL AGENTS | BRITISH TECH GROUP INT (GB) | 1999-04-28 | — | — | EP | disclosed |