Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 6/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | F10 | P00742 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 4/20 | 0.42 |
| ▸ | CA9 | Q16790 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8059467 | 0.99 | CA2 (0.42) | CA2TSHRF10CA1CA9 | |
| SCHEMBL8068683 | 0.92 | SMN1; SMN2 (0.41) | TSHRF10KDM4EMAPTMRGPRX1 | |
| Hydrochloric Acid SCHEMBL8059609 | 0.91 | SMN1; SMN2 (0.40) | TSHRF10KDM4EMAPTMRGPRX1 | |
| SCHEMBL8743801 | 0.89 | PARP10 (0.40) | TSHRF10MRGPRX1HTT | |
| SCHEMBL8379266 | 0.89 | HPGD (0.41) | CA2TSHRF10CA1CA9 | |
| SCHEMBL8743804 | 0.88 | KMT2A (0.41) | F10ALDH1A1KMT2AHTT | |
| Hydrochloric Acid SCHEMBL8743791 | 0.88 | PARP10 (0.40) | F10MRGPRX1 | |
| SCHEMBL8743793 | 0.88 | MRGPRX1 (0.44) | CA2F10CA1CA9MRGPRX1 | |
| Hydrochloric Acid SCHEMBL8374986 | 0.88 | HPGD (0.40) | CA2TSHRF10CA1CA9 | |
| SCHEMBL8499411 | 0.87 | GCK (0.42) | F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0723956-B1 | Basically substituted benzoylguanidines, process for their preparation, their use as medicaments or diagnostics as well as medicaments containing them | HOECHST AG (DE) | 1999-10-13 | — | — | EP | disclosed |
| EP-0723956-A1 | Basically substituted benzoylguanidines, process for their preparation, their use as medicaments or diagnostics as well as medicaments containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-07-31 | — | — | EP | disclosed |