Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC15A1 | P46059 | 2/20 | 0.59 |
| ▸ | SLC1A1 | P43005 | 5/20 | 0.54 |
| ▸ | SLC1A3 | P43003 | 4/20 | 0.54 |
| ▸ | SLC1A2 | P43004 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | CDC25B | P30305 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | LAP3 | P28838 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9781868 | 1.00 | SLC15A1 (0.59) | SLC15A1SLC1A1SLC1A3SLC1A2KMT2A | |
| SCHEMBL27635124 | 1.00 | SLC15A1 (0.59) | SLC15A1SLC1A1SLC1A3SLC1A2KMT2A | |
| SCHEMBL27713444 | 0.91 | SLC15A1 (0.56) | SLC15A1SLC1A1SLC1A3SLC1A2KMT2A | |
| SCHEMBL6546883 | 0.83 | ALDH1A1 (0.59) | SLC15A1SLC1A1SLC1A3SLC1A2KMT2A | |
| Hydrochloric Acid SCHEMBL27518479 | 0.83 | ALDH1A1 (0.59) | SLC15A1SLC1A1SLC1A3SLC1A2KMT2A | |
| SCHEMBL22804119 | 0.83 | SLC15A1 (0.65) | SLC15A1SLC1A1SLC1A3SLC1A2KMT2A | |
| SCHEMBL1241916 | 0.83 | SLC15A1 (0.65) | SLC15A1SLC1A1SLC1A3SLC1A2KMT2A | |
| SCHEMBL4523936 | 0.82 | SLC15A1 (0.65) | SLC15A1SLC1A1SLC1A3SLC1A2KMT2A | |
| SCHEMBL5898461 | 0.82 | SLC15A1 (0.65) | SLC15A1SLC1A1SLC1A3SLC1A2KMT2A | |
| SCHEMBL730848 | 0.82 | SLC15A1 (0.65) | SLC15A1SLC1A1SLC1A3SLC1A2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250313574-A1 | SIALIC ACID DERIVATIVES AND METHODS OF USING SAME | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2025-10-09 | — | — | US | disclosed |
| EP-4536653-A2 | SIALIC ACID DERIVATIVES AND METHODS OF USING SAME | Eisai R&D Management Co., Ltd. (JP) | 2025-04-16 | — | — | EP | disclosed |
| US-20250002495-A1 | SPIRO-LACTAM NMDA MODULATORS AND METHODS OF USING SAME | TENACIA BIOTECHNOLOGY HONG KONG CO LTD (HK) | 2025-01-02 | — | — | US | disclosed |
| US-12157736-B2 | Spiro-lactam NMDA modulators and methods of using same | TENACIA BIOTECHNOLOGY (HONG KONG) CO., LIMITED (HK) | 2024-12-03 | — | — | US | disclosed |
| US-20240300951-A1 | Pyrazolopyridinone Compounds | BEIGENE LTD. (KY) | 2024-09-12 | — | — | US | disclosed |
| US-12084444-B2 | Spiro-lactam NMDA modulators and methods of using same | TENACIA BIOTECHNOLOGY (HONG KONG) CO., LIMITED (CN) | 2024-09-10 | — | — | US | disclosed |
| US-20240270751-A1 | Pyrazolopyridinone Compounds | BEIGENE LTD. (KY) | 2024-08-15 | — | — | US | disclosed |
| CN-117836296-A | Pyrazolopyridone compounds | 百济神州有限公司 | 2024-04-05 | — | — | CN | disclosed |
| WO-2024054919-A1 | SPIRO-LACTAM NMDA RECEPTOR MODULATORS AND USES THEREOF | TENACIA BIOTECHNOLOGY (HONG KONG) CO., LIMITED (CN) | 2024-03-14 | — | — | WO | disclosed |
| EP-3490994-B1 | SPIRO-LACTAM AND BIS-SPIRO-LACTAM NMDA RECEPTOR MODULATORS AND USES THEREOF | APTINYX INC (US) | 2024-02-07 | — | — | EP | disclosed |
| US-20180258139-A1 | N-METHYL-D-ASPARTATE RECEPTOR MODULATORS AND METHODS OF MAKING AND USING SAME | NAUREX INC (US) | 2018-09-13 | — | — | US | disclosed |
| US-9994614-B2 | N-methyl-D-aspartate receptor modulators and methods of making and using same | NAUREX, INC. (US) | 2018-06-12 | — | — | US | disclosed |
| WO-2018026792-A1 | SPIRO-LACTAM AND BIS-SPIRO-LACTAM NMDA RECEPTOR MODULATORS AND USES THEREOF | APTINYX INC. (US) | 2018-02-08 | — | — | WO | disclosed |
| US-20170210779-A1 | N-METHYL-D-ASPARTATE RECEPTOR MODULATORS AND METHODS OF MAKING AND USING SAME | NAUREX INC (US) | 2017-07-27 | — | — | US | disclosed |
| EP-3171941-A1 | N-METHYL-D-ASPARTATE RECEPTOR MODULATORS AND METHODS OF MAKING AND USING SAME | Naurex Inc. (US) | 2017-05-31 | — | — | EP | disclosed |
| WO-2016014982-A1 | N-METHYL-D-ASPARTATE RECEPTOR MODULATORS AND METHODS OF MAKING AND USING SAME | NAUREX, INC. (US) | 2016-01-28 | — | — | WO | disclosed |
| EP-0665229-B1 | Process for the production of nucleic acid base derivatives | AJINOMOTO KK (JP) | 1999-11-17 | — | — | EP | disclosed |
| EP-0665229-A1 | Process for the production of nucleic acid base derivatives | Ajinomoto Co., Inc. (JP) | 1995-08-02 | — | — | EP | disclosed |
| US-4500726-A | IN PRESENCE OF PHASE TRANSFER AGENT | PPG INDUSTRIES, INC. (US) | 1985-02-19 | — | — | US | disclosed |
| US-4484001-A | LIQUID PHASE BLOCKING OF AMINO ACIDS BY A BENZYL HALOFORMATE USING CROWN COMPOUND PHASE TRANSFER AGENTS | PPG INDUSTRIES, INC. (US) | 1984-11-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180258139-A1 | N-METHYL-D-ASPARTATE RECEPTOR MODULATORS AND METHODS OF MAKING AND USING SAME | GRIN1, GRIN2A, GRIN3A | SLC15A1 1260/4885SLC1A1 41/4885SLC1A3 51/4885 |
| US-20250313574-A1 | SIALIC ACID DERIVATIVES AND METHODS OF USING SAME | NEU1, NEU2, NEU4 | SLC15A1 846/4885SLC1A1 267/4885SLC1A3 312/4885 |
| US-20170210779-A1 | N-METHYL-D-ASPARTATE RECEPTOR MODULATORS AND METHODS OF MAKING AND USING SAME | GRIN1, GRIN2A, GRIN3A | SLC15A1 1260/4885SLC1A1 41/4885SLC1A3 51/4885 |
| US-20240300951-A1 | Pyrazolopyridinone Compounds | NFATC1, CD4, PBK | SLC15A1 4547/4885SLC1A1 4726/4885SLC1A3 4818/4885 |
| US-20240270751-A1 | Pyrazolopyridinone Compounds | NFATC1, CD4, PBK | SLC15A1 4547/4885SLC1A1 4726/4885SLC1A3 4818/4885 |
| US-12084444-B2 | Spiro-lactam NMDA modulators and methods of using same | GRIN1, GRIN2A, GRIN2C | SLC15A1 947/4885SLC1A1 42/4885SLC1A3 51/4885 |
| US-20250002495-A1 | SPIRO-LACTAM NMDA MODULATORS AND METHODS OF USING SAME | GRIN1, GRIN2A, GRIN2C | SLC15A1 947/4885SLC1A1 42/4885SLC1A3 51/4885 |
| US-12157736-B2 | Spiro-lactam NMDA modulators and methods of using same | GRIN1, GRIN2A, GRIN2C | SLC15A1 947/4885SLC1A1 42/4885SLC1A3 51/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.