Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 15/20 | 0.49 |
| ▸ | MMP1 | P03956 | 14/20 | 0.49 |
| ▸ | ADAM17 | P78536 | 13/20 | 0.49 |
| ▸ | MMP13 | P45452 | 13/20 | 0.49 |
| ▸ | MMP2 | P08253 | 5/20 | 0.38 |
| ▸ | MMP7 | P09237 | 3/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | MMP3 | P08254 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8446283 | 0.89 | MMP9 (0.47) | MMP9MMP1ADAM17MMP13MMP2 | |
| SCHEMBL8445810 | 0.87 | MMP9 (0.46) | MMP9MMP1ADAM17MMP13MMP2 | |
| SCHEMBL8448311 | 0.84 | MMP9 (0.45) | MMP9MMP1ADAM17MMP13MMP2 | |
| SCHEMBL8448394 | 0.84 | MMP9 (0.67) | MMP9MMP1ADAM17MMP13MMP2 | |
| SCHEMBL8450948 | 0.79 | HTT (0.39) | MMP9MMP1ADAM17MMP13 | |
| SCHEMBL8445657 | 0.74 | MMP9 (0.48) | MMP9MMP1ADAM17MMP13 | |
| SCHEMBL8446520 | 0.74 | CA12 (0.33) | MMP9MMP1ADAM17MMP13 | |
| SCHEMBL8446284 | 0.73 | MMP9 (0.59) | MMP9MMP1ADAM17MMP13MMP2 | |
| SCHEMBL8448761 | 0.72 | MMP9 (0.46) | MMP9MMP1MMP13MMP2MMP7 | |
| SCHEMBL8446650 | 0.71 | CA12 (0.38) | MMP9MMP1ADAM17MMP13MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0915086-A1 | PHENYLSULFONAMIDE DERIVATIVES | ONO PHARMACEUTICAL CO., LTD. (JP) | 1999-05-12 | — | — | EP | claimed |
| EP-0915086-A1 | PHENYLSULFONAMIDE DERIVATIVES | ONO PHARMACEUTICAL CO., LTD. (JP) | 1999-05-12 | — | — | EP | disclosed |