Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 3/20 | 0.48 |
| ▸ | ADAM17 | P78536 | 3/20 | 0.48 |
| ▸ | MMP1 | P03956 | 3/20 | 0.48 |
| ▸ | MMP13 | P45452 | 2/20 | 0.48 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.46 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | AGER | Q15109 | 1/20 | 0.37 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.37 |
| ▸ | BMP1 | P13497 | 2/20 | 0.36 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8445759 | 0.87 | MMP9 (0.54) | MMP9ADAM17MMP1MMP13ADAMTS4 | |
| SCHEMBL8446545 | 0.85 | ADAMTS4 (0.48) | MMP9ADAM17MMP1MMP13ADAMTS4 | |
| SCHEMBL8448394 | 0.85 | MMP9 (0.67) | MMP9ADAM17MMP1MMP13ADAMTS4 | |
| SCHEMBL8446538 | 0.82 | MMP13 (0.44) | MMP9ADAM17MMP1MMP13ADAMTS4 | |
| SCHEMBL10911759 | 0.80 | AGER (0.59) | MMP9MMP1MMP13ADAMTS4KEAP1 | |
| SCHEMBL12907960 | 0.79 | ADAMTS4 (0.58) | MMP9MMP13ADAMTS4KEAP1NFE2L2 | |
| SCHEMBL14798295 | 0.79 | ADAMTS4 (0.58) | MMP9MMP13ADAMTS4KEAP1NFE2L2 | |
| SCHEMBL6499544 | 0.79 | ADAM17 (0.77) | MMP9ADAM17MMP1MMP13 | |
| SCHEMBL16894214 | 0.78 | ADAMTS4 (0.50) | MMP9MMP1MMP13ADAMTS4KEAP1 | |
| SCHEMBL16894216 | 0.78 | ADAMTS4 (0.50) | MMP9MMP1MMP13ADAMTS4KEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0915086-A1 | PHENYLSULFONAMIDE DERIVATIVES | ONO PHARMACEUTICAL CO., LTD. (JP) | 1999-05-12 | — | — | EP | claimed |
| EP-0915086-A1 | PHENYLSULFONAMIDE DERIVATIVES | ONO PHARMACEUTICAL CO., LTD. (JP) | 1999-05-12 | — | — | EP | disclosed |