Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 9/20 | 0.46 |
| ▸ | MMP13 | P45452 | 9/20 | 0.46 |
| ▸ | MMP1 | P03956 | 7/20 | 0.46 |
| ▸ | ADAM17 | P78536 | 5/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 5/20 | 0.36 |
| ▸ | MMP3 | P08254 | 2/20 | 0.36 |
| ▸ | MMP7 | P09237 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MMP8 | P22894 | 3/20 | 0.35 |
| ▸ | BMP1 | P13497 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8448391 | 0.87 | MMP9 (0.49) | MMP9MMP13MMP1ADAM17MMP2 | |
| SCHEMBL8446283 | 0.86 | MMP9 (0.47) | MMP9MMP13MMP1ADAM17CA12 | |
| SCHEMBL8445813 | 0.83 | MMP9 (0.62) | MMP9MMP13MMP1ADAM17CYP2C9 | |
| SCHEMBL8448311 | 0.82 | MMP9 (0.45) | MMP9MMP13MMP1ADAM17MMP2 | |
| SCHEMBL8450948 | 0.76 | HTT (0.39) | MMP9MMP13MMP1ADAM17CYP2C9 | |
| SCHEMBL8446545 | 0.73 | ADAMTS4 (0.48) | MMP9MMP13MMP1ADAM17CYP2C9 | |
| SCHEMBL8446537 | 0.72 | CA12 (0.44) | CYP2C9CA12CA1CA2CA4 | |
| SCHEMBL8446541 | 0.70 | MMP1 (0.60) | MMP9MMP13MMP1ADAM17CYP2C9 | |
| SCHEMBL18946200 | 0.70 | CA12 (0.55) | CYP2C9CA12CA1CA2CA4 | |
| SCHEMBL8448904 | 0.70 | DUT (0.44) | MMP9MMP13MMP1ADAM17CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0915086-A1 | PHENYLSULFONAMIDE DERIVATIVES | ONO PHARMACEUTICAL CO., LTD. (JP) | 1999-05-12 | — | — | EP | claimed |
| EP-0915086-A1 | PHENYLSULFONAMIDE DERIVATIVES | ONO PHARMACEUTICAL CO., LTD. (JP) | 1999-05-12 | — | — | EP | disclosed |