Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.60 |
| ▸ | MMP9 | P14780 | 5/20 | 0.57 |
| ▸ | MMP2 | P08253 | 5/20 | 0.57 |
| ▸ | MMP1 | P03956 | 4/20 | 0.57 |
| ▸ | MMP13 | P45452 | 4/20 | 0.57 |
| ▸ | MMP3 | P08254 | 3/20 | 0.57 |
| ▸ | MMP7 | P09237 | 3/20 | 0.57 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.54 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.54 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 2/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | MMP8 | P22894 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8448539 | 1.00 | ADAMTS4 (0.60) | ADAMTS4MMP9MMP2MMP1MMP13 | |
| SCHEMBL4975578 | 0.91 | ADAMTS4 (0.71) | ADAMTS4MMP9MMP2MMP1MMP13 | |
| SCHEMBL698908 | 0.91 | ADAMTS4 (0.71) | ADAMTS4MMP9MMP2MMP1MMP13 | |
| SCHEMBL698907 | 0.91 | ADAMTS4 (0.71) | ADAMTS4MMP9MMP2MMP1MMP13 | |
| Water SCHEMBL29881522 | 0.89 | ADAMTS4 (0.69) | ADAMTS4MMP9MMP2MMP1MMP13 | |
| SCHEMBL25195705 | 0.88 | MAPT (0.58) | ADAMTS4MMP9MMP2MMP1MMP13 | |
| SCHEMBL25265502 | 0.88 | MAPT (0.58) | ADAMTS4MMP9MMP2MMP1MMP13 | |
| SCHEMBL8445775 | 0.87 | HSD17B10 (0.55) | MMP9MMP2MMP1MMP13MMP3 | |
| SCHEMBL13074225 | 0.83 | MMP2 (0.68) | ADAMTS4MMP9MMP2MMP1MMP13 | |
| SCHEMBL8449004 | 0.82 | MMP9 (0.75) | ADAMTS4MMP9MMP2MMP1MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0915086-A1 | PHENYLSULFONAMIDE DERIVATIVES | ONO PHARMACEUTICAL CO., LTD. (JP) | 1999-05-12 | — | — | EP | claimed |
| EP-0915086-A1 | PHENYLSULFONAMIDE DERIVATIVES | ONO PHARMACEUTICAL CO., LTD. (JP) | 1999-05-12 | — | — | EP | disclosed |