Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 7/20 | 0.33 |
| ▸ | ESR1 | P03372 | 6/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | PRKDC | P78527 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | ATR | Q13535 | 1/20 | 0.30 |
| ▸ | ATRIP | Q8WXE1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8447729 | 0.84 | ESR2 (0.36) | ESR2ESR1CYP3A4CYP2C9DGAT1 | |
| SCHEMBL8453687 | 0.83 | DRD2 (0.38) | ESR2ESR1CYP3A4CYP2C9DGAT1 | |
| SCHEMBL8452629 | 0.83 | ESR2 (0.35) | ESR2ESR1CYP3A4CYP2C9DGAT1 | |
| SCHEMBL8456906 | 0.82 | HTR2C (0.46) | ESR2DGAT1 | |
| SCHEMBL8447595 | 0.81 | GPR84 (0.34) | — | |
| SCHEMBL8451655 | 0.81 | SPHK1 (0.34) | ESR2ESR1CYP3A4CYP2C9DGAT1 | |
| SCHEMBL8447998 | 0.80 | HRH3 (0.40) | ESR2ESR1CYP3A4CYP2C9 | |
| SCHEMBL8456323 | 0.80 | ESR2 (0.33) | ESR2ESR1CYP3A4CYP2C9DGAT1 | |
| SCHEMBL8449373 | 0.80 | CYP17A1 (0.36) | ESR2ESR1CYP3A4CYP2C9DGAT1 | |
| SCHEMBL8454721 | 0.78 | SPHK1 (0.41) | CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0679707-B1 | Liquid crystalline compound, liquid crystal composition and liquid crystal display element | CHISSO CORP (JP) | 1999-06-16 | — | — | EP | disclosed |
| US-5720899-A | Liquid crystalline compound, liquid crystal composition and liquid crystal display element | CHISSO CORPORATION (JP) | 1998-02-24 | — | — | US | disclosed |
| US-5653911-A | Liquid crystalline compound liquid crystal composition and liquid crystal display element | CHISSO CORPORATION (JP) | 1997-08-05 | — | — | US | disclosed |
| EP-0679707-A1 | Liquid crystalline compound, liquid crystal composition and liquid crystal display element | Chisso Corporation (JP) | 1995-11-02 | — | — | EP | disclosed |