Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.53 |
| ▸ | MMP9 | P14780 | 4/20 | 0.51 |
| ▸ | MMP1 | P03956 | 2/20 | 0.51 |
| ▸ | MMP2 | P08253 | 2/20 | 0.51 |
| ▸ | MMP3 | P08254 | 2/20 | 0.51 |
| ▸ | MMP7 | P09237 | 2/20 | 0.51 |
| ▸ | MMP13 | P45452 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.49 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.49 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.48 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.48 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.48 |
| ▸ | EGFR | P00533 | 3/20 | 0.46 |
| ▸ | ERBB2 | P04626 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL698907 | 0.85 | ADAMTS4 (0.71) | TDP1ADAMTS4MMP9MMP1MMP2 | |
| SCHEMBL698908 | 0.85 | ADAMTS4 (0.71) | TDP1ADAMTS4MMP9MMP1MMP2 | |
| SCHEMBL4975578 | 0.85 | ADAMTS4 (0.71) | TDP1ADAMTS4MMP9MMP1MMP2 | |
| Water SCHEMBL29881522 | 0.83 | ADAMTS4 (0.69) | TDP1ADAMTS4MMP9MMP1MMP2 | |
| SCHEMBL8448862 | 0.80 | TDP1 (0.57) | TDP1ADAMTS4MMP9MMP1MMP2 | |
| SCHEMBL7674729 | 0.78 | MMP9 (0.66) | ADAMTS4MMP9MMP1MMP2MMP3 | |
| SCHEMBL7866928 | 0.78 | NPC1 (0.51) | TDP1NPC1RAB9AL3MBTL1ALDH1A1 | |
| SCHEMBL8448539 | 0.77 | ADAMTS4 (0.60) | TDP1ADAMTS4MMP9MMP1MMP2 | |
| SCHEMBL8448545 | 0.77 | ADAMTS4 (0.60) | TDP1ADAMTS4MMP9MMP1MMP2 | |
| SCHEMBL6793899 | 0.77 | ADAMTS4 (0.60) | TDP1ADAMTS4MMP9MMP1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0915086-A1 | PHENYLSULFONAMIDE DERIVATIVES | ONO PHARMACEUTICAL CO., LTD. (JP) | 1999-05-12 | — | — | EP | disclosed |